Table 1 of
Lu, Mol Vis 2007;
13:1154-1160.
Table 1. Results from genome-wide linkage screening in Family 1
The maximum non-parametric linkage score (NPL) and logarithm of odds score (LOD) were summarized in this table. Five linkage-peak regions were identified in chromosomes 1, 3, 4, 15, and 17. The flanking single nucleotide polymorphisms (SNPs) of each linkage-peak interval were shown in "flanking SNPs" column. Additional microsatellite markers were selected for genotyping in the five regions.
Affymetrix 10 K chip Linkage-peak interval Microsatellite markers selected Chromosome -------------------- ---------------------- from linkage peak region for number Max NPL Max LOD flanking SNPs size genotyping and further mapping ---------- ------- ------- ---------------------- ----- ----------------------------------- 1 4.9 1.8 rs3122425 to rs2341709 57 Mb D1S2130, S2134, S1669, S1665, S1728, S551, S1588 3 4.9 1.8 rs1822813 to rs2138212 80 Mb D3S2409, S1766, S1285, S2406, S2465, S2459, S3045, S2460, ATA28H11 4 4.6 1.8 rs2866796 to rs1388070 48 Mb D4S2623, S2394, S1644, S1625, S1629 15 4.9 1.8 rs1964562 to rs2380165 13 Mb D15S653, S652 17 4.6 1.8 rs718993 to rs1320283 30 Mb D17S921, S805, S1294, S1293, S966, S1299, S1868, S787 |