Figure 1 of Guyon, Mol Vis 2007; 13:1094-1105.

Figure 1. Pedigree of XLPRA1 affected dogs

H2 is a purebred Siberian husky founder that was outcrossed to dogs from various breeds. Those dog breeds contributing to the pedigree include Irish setter, Alaskan malamute, miniature schnauzer, and poodle. Severely affected dogs are in black, moderately affected dogs in dark grey, and mildly affected dogs in crosshatch pattern. Squares represent male and circles represent female. All affected males are hemizygous; affected females H59 and H64 are homozygous for the mutation. Dotted circles are carrier females that were not included in the phenotype analysis. The following abbreviations were used: (B) purebred beagle, (N) mixed breed control, and (E) Norwegian elkhound-derived outcross.

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Guyon, Mol Vis 2007; 13:1094-1105 <>
©2007 Molecular Vision <>
ISSN 1090-0535