Figure 3. Effect of minocycline and sulforaphane on lipopolysaccharide-induced nitrite and nitrate release in cultured retinal microglial cells

A: Release of nitrite and nitrate from cultured retinal microglia with LPS treatment. The increment of nitrite and nitrate levels became significant after 6 h of LPS treatment and continued for up to 24 h. B: Administration of minocycline significantly reduced LPS-induced nitrite and nitrate production in retinal microglial cells. C: Administration of sulforaphane significantly reduced LPS-induced nitrite and nitrate production in retinal microglial cells. Data represented four independent experiments and were expressed as mean±SD. Asterisk indicates p<0.01 is considered significant.