Figure 7.

Immunohistochemistry in mechanically-injured mice conjunctiva. Invasion of F4/80-labeled macrophages (A) and VEGF (B) and αSMA (C) expression by fibroblasts were both lower in the Smad7-Ad treated group as compared with those in control group. The numbers of F4/80-positive macrophages were significantly lower in Smad7-Ad treated group than in Cre-Ad control group, while there was no significant difference on day 30 (D). In Panel D, the asterisk indicates a p<0.05, the double asterisk indicates a p<0.01, and NS means nonsignificant.