Table 3 of
Seitsonen, Mol Vis 2006;
12:796-801.Table 3 of
Seitsonen, Mol Vis 2006;
12:796-801.
Table 3. Allele and genotype frequencies and results of association tests of the Met299Val polymorphism in the elongation of very long chain fatty acids-like 4 gene
The genotype and allele frequencies are shown for cases and controls (A). Familial and sporadic age-related macular degeneration (AMD) cases are compared to non-AMD controls (B) and blood donor controls (C) for the Met299Val polymorphism in the elongation of very long chain fatty acids-like 4 (ELOVL4) gene. The p values, odds ratios (ORs), and confidence intervals (CI) are for the comparision of familial and sporadic AMD cases to non-AMD and blood donor controls within each group.
A:
Blood
Familial Sporadic Non-AMD donor
cases cases controls controls
(n=181) (n=154) (n=105) (n=350)
-------- -------- -------- -------- --------
Genotype
A/A 0.809 0.868 0.845 0.811
A/G 0.191 0.132 0.155 0.180
G/G 0.000 0.000 0.000 0.009
Allele
A 0.904 0.934 0.922 0.901
G 0.096 0.066 0.078 0.099
|
B:
Comparison Familial cases Sporadic cases -------------- ------------------ ----------------- A/A versus A/G OR (95% CI) 0.779 (0.406-1.49) 1.21 (0.596-2.47) p value 0.451 0.593 A versus G OR (95% CI) 0.798 (0.429-1.48) 1.20 (0.604-2.37) p value 0.474 0.607 |
C:
Comparison Familial cases Sporadic cases -------------- ------------------ ----------------- A/A versus A/G OR (95% CI) 0.940 (0.591-1.49) 1.46 (0.850-2.52) p value 0.792 0.168 A versus G OR (95% CI) 1.04 (0.672-1.60) 1.55 (0.926-2.60) p value 0.874 0.0931 |