Table 9 of
Liton, Mol Vis 2006;
12:774-790.Table 9 of
Liton, Mol Vis 2006;
12:774-790.
Table 9.
List of the genes downregulated in cultured human trabecular meshwork (HTM) mapping in glaucoma loci.
Unigene
Locus Gene Unigene ID cluster
-------- -------------------------------------------------- ------------- ----------
GLC1A Activating transcription factor 6 ATF6 Hs.433046
ATPase, Na+/K+ transporting, alpha 2 (+) ATP1A2 Hs.34114
polypeptide
AV712694 DCA Homo sapiens cDNA clone DCAAJG07 5', KIFAP3
mRNA sequence.
CD1D antigen, d polypeptide CD1D Hs.1799
CDNA FLJ13332 fis, clone OVARC1001813 Hs.225093
Coagulation factor V (proaccelerin, labile factor) F5 Hs.30054
DnaJ (Hsp40) homolog, subfamily C, member 6 DNAJC6 Hs.129587
Expressed in hematopoietic cells, heart, liver HHL Hs.495257
Fc fragment of IgE, high affinity I, receptor for; FCER1G Hs.433300
gamma polypeptide
Fc fragment of IgG, low affinity IIa, receptor for FCGR2A Hs.352642
(CD32)
Fc fragment of IgG, low affinity IIb, receptor for FCGR2B Hs.126384
(CD32)
FLJ45235 protein FLJ45235 Hs.130054
Homo sapiens Fc fragment of IgE, high affinity I, FCER1G
receptor for; gamma polypeptide, mRNA (cDNA clone
MGC:22620 IMAGE:4704425), complete cds.
Hypothetical protein FLJ10287 FLJ10287 Hs.40337
Hypothetical protein FLJ20442 FLJ20442 Hs.425801
Hypothetical protein LOC57821 LOC57821 Hs.130746
Hypothetical protein MGC21854 MGC21854 Hs.233125
Lamina-associated polypeptide 1B LAP1B Hs.234265
Mitochondrial ribosomal protein S14 MRPS14 Hs.247324
Myocilin, trabecular meshwork inducible MYOC Hs.78454
glucocorticoid response
Selectin L (lymphocyte adhesion molecule 1) SELL Hs.82848
SPT3-associated factor 42 STAF42 Hs.435967
Tenascin N TNN Hs.156369
Torsin family 3, member A TOR3A Hs.26267
Vang-like 2 (van gogh, Drosophila) VANGL2 Hs.137507
Vesicle-associated membrane protein 4 VAMP4 Hs.6651
V-ski sarcoma viral oncogene homolog (avian) SKI Hs.2969
Wa37f07.x1 NCI_CGAP_Kid11 Homo sapiens cDNA clone DNM3
IMAGE:2300293 3', mRNA sequence.
GLC1B NCK adaptor protein 2 NCK2 Hs.101695
Pleckstrin homology, Sec7 and coiled-coil domains, PSCDBP Hs.270
binding protein
POU domain, class 3, transcription factor 3 POU3F3 Hs.248158
RAN binding protein 2 RANBP2 Hs.199179
RAN binding protein 2-like 1 GCC2 Hs.434959
REV1-like (yeast) REV1L Hs.443077
Ribosomal protein L31 TBC1D8 Hs.375921
Transcribed sequence with strong similarity to DKFZp686P0288 Hs.516168
protein prf:2115329A (H.sapiens) 2115329A
nucleoprotein Nup358 [Homo sapiens]
Unc-50 homolog (C. elegans) UNC50 Hs.13370
GLC1C ATPase, Ca++ transporting, type 2C, member 1 ATP2C1 Hs.106778
B aggressive lymphoma gene BAL Hs.131315
CD86 antigen (CD28 antigen ligand 2, B7-2 antigen) CD86 Hs.27954
Ceruloplasmin (ferroxidase) CP Hs.282557
disrupted in renal carcinoma 2 DIRC2 Hs.11360
EphB1 EPHB1 Hs.272311
G protein-coupled receptor 105 GPR105 Hs.2465
General transcription factor IIE, polypeptide 1, GTF2E1 Hs.145381
alpha 56 kDa
Hermansky-Pudlak syndrome 3 CP Hs.282804
HSPC056 protein HSPC056 Hs.102708
Hypothetical protein FLJ10546 FLJ10546 Hs.518278
Hypothetical protein FLJ10618 FLJ10618 Hs.144130
Hypothetical protein FLJ23751 FLJ23751 Hs.312930
Hypothetical protein LOC132241 LOC132241 Hs.437334
Hypothetical protein MGC3040 MGC3040 Hs.280740
Integrin, beta 5 ITGB5 Hs.149846
KIAA0779 protein KIAA0779 Hs.362996
Kruppel-like factor 15 KLF15 Hs.272215
Oxysterol binding protein-like 11 OSBPL11 Hs.61260
Pphospholipid scramblase 1 PLSCR1 Hs.348478
Protein phosphatase 2 (formerly 2A), regulatory PPP2R3A Hs.133234
subunit B'', alpha
Purinergic receptor P2Y, G-protein coupled, 12 P2RY12 Hs.444983
Rhysin 2 BBAP Hs.334875
Ribosomal protein S6 kinase, 90 kDa, polypeptide 1 RPS6KA1 Hs.149957
Serine/threonine kinase with Dbl- and pleckstrin TRAD Hs.162189
homology domains
Solute carrier family 15 (H+/peptide transporter), SLC15A2 Hs.118747
member 2
Sorting nexin 4 SNX4 Hs.267812
Transcription factor Dp-2 (E2F dimerization TFDP2 Hs.379018
partner 2)
Transmembrane protein 22 TMEM22 Hs.101257
Zinc finger protein 148 (pHZ-52) ZNF148 Hs.442787
Zinc finger protein 9 (a cellular retroviral ZNF9 Hs.2110
nucleic acid binding protein)
GLC1D Angiopoietin 1 ANGPT1 Hs.2463
Hypothetical protein MGC35555 MGC35555 Hs.209569
Proenkephalin PENK Hs.339831
GLC1E Adenovirus 5 E1A binding protein ZMYND11 Hs.145894
Coiled-coil domain containing 3 CCDC3 Hs.107253
DNA-damage-inducible transcript 4 DDIT4 Hs.111244
GLC1F CDNA clone IMAGE:6183232, partial cds Hs.491104
CDNA FLJ46106 fis, clone TESTI2026284 Hs.308222
df18g11.y1 Morton Fetal Cochlea Homo sapiens cDNA
clone IMAGE:2483901 5', mRNA sequence.
DnaJ (Hsp40) homolog, subfamily B, member 6 DNAJB6 Hs.181195
Hepatocellular carcinoma-associated antigen 112 HCA112 Hs.12126
Human immune associated nucleotide 2 hIAN2 Hs.105468
Immune associated nucleotide hIAN7 Hs.124675
Immune associated nucleotide 4 like 1 (mouse) IAN4L1 Hs.412331
Immunity associated protein 4 HIMAP4 Hs.30822
KIAA1718 protein KIAA1718 Hs.222707
LR8 protein LR8 Hs.190161
Protein tyrosine phosphatase, receptor type, N PTPRN2 Hs.74624
polypeptide 2
SWI/SNF related, matrix associated, actin SMARCD3 Hs.444445
dependent regulator of chromatin, subfamily d,
member 3
Th95b11.x1 Soares_NSF_F8_9W_OT_PA_P_S1 Homo IAN4L1
sapiens cDNA clone IMAGE:2126397 3', mRNA
sequence.
Tt37g06.x1 NCI_CGAP_GC6 Homo sapiens cDNA clone hIAN6
IMAGE:2243002 3' similar to contains MER13.t1
MER13 repetitive element, mRNA sequence.
Wp61g11.x1 NCI_CGAP_Brn25 Homo sapiens cDNA clone LOC154761
IMAGE:2466308 3', mRNA sequence.
Zinc finger protein 212 ZNF212 Hs.108139
GLC1G 601661186R1 NIH_MGC_72 Homo sapiens cDNA clone MCC
IMAGE:3916173 3', mRNA sequence.
APG12 autophagy 12-like (S. cerevisiae) APG12L Hs.264482
COMM domain containing 10 COMMD10 Hs.151458
Cysteine dioxygenase, type I CDO1 Hs.442378
Decapping enzyme hDcp2 DCP2 Hs.442039
Glutathione peroxidase 3 (plasma) GPX3 Hs.386793
Praja 2, RING-H2 motif containing PJA2 Hs.224262
Sema domain, transmembrane domain (TM), and SEMA6A Hs.443012
Cytoplasmic domain, (semaphorin) 6A
TIGA1 TIGA1 Hs.12082
Tripartite motif-containing 36 TRIM36 Hs.429642
Ubiquitin-conjugating enzyme E2B (RAD6 homolog) UBE2B Hs.385986
GLC3A Adenylate cyclase 3 ADCY3 Hs.188402
Baculoviral IAP repeat-containing 6 (apollon) BIRC6 Hs.360026
Chromosome 2 open reading frame 8 C2orf8 Hs.368545
Human Tis11d gene, complete cds. ZFP36L2
Hypothetical protein MGC33926 MGC33926 Hs.40808
Solute carrier family 8 (sodium/calcium SLC8A1 Hs.144465
exchanger), member 1
GLC3B Angiopoietin-like factor CDT6 Hs.146559
Calmodulin binding transcription activator 1 CAMTA1 Hs.253254
Chloride channel Kb CLCNKA Hs.352243
Collagen, type XVI, alpha 1 COL16A1 Hs.26208
Complement component 1, q subcomponent, alpha C1QA Hs.9641
polypeptide
Complement component 1, q subcomponent, beta C1QB Hs.8986
polypeptide
DnaJ (Hsp40) homolog, subfamily C, member 6 DNAJC6 Hs.129587
Gardner-Rasheed feline sarcoma viral (v-fgr) FGR Hs.1422
oncogene homolog
Hc93h01.x1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA IL28RA
clone IMAGE:2907601 3' similar to contains element
MER30 repetitive element, mRNA sequence.
Heterogeneous nuclear ribonucleoprotein R HNRPR Hs.15265
Homo sapiens cDNA clone MGC:1167 IMAGE:3536204, ATPIF1
complete cds.
Hypothetical protein BC007899 LOC148898 Hs.61884
Hypothetical protein FLJ10287 FLJ10287 Hs.40337
Hypothetical protein MGC34648 MGC34648 Hs.96607
Kinesin family member 1B KIF1B Hs.444757
LOC388610 (LOC388610), mRNA Hs.355747
Mitochondrial ribosomal protein L20 MRPL20 Hs.182698
MRNA; cDNA DKFZp667N1113 (from clone RSC1A1 Hs.24183
DKFZp667N1113)
Period homolog 3 (Drosophila) PER3 Hs.418036
Phosphatidic acid phosphatase type 2B PPAP2B Hs.525620
Phospholipase A2, group IIA (platelets, synovial PLA2G2A Hs.76422
fluid)
Phospholipase A2, group V PLA2G5 Hs.319438
Protein tyrosine phosphatase type IVA, member 2 PTP4A2 Hs.82911
Qe51c05.x1 Soares_fetal_lung_NbHL19W Homo sapiens C1QG
cDNA clone IMAGE:1742504 3' similar to
SW:C1QC_HUMAN P02747 COMPLEMENT C1Q SUBCOMPONENT,
C CHAIN PRECURSOR; mRNA sequence.
Retinoid binding protein 7 RBP7 Hs.422688
Similar to RIKEN cDNA F730108M23 gene (LOC400734), GPR157 Hs.31181
mRNA
SMART/HDAC1 associated repressor protein SHARP Hs.184245
Solute carrier family 2 (facilitated SLC2A5 Hs.33084
glucose/fructose transporter), member 5
Synonym: TDP-43; TAR DNA-binding protein-43; TARDBP
go_component: nucleus [goid 0005634; evidence
TAS; pmid 7745706]; go_function: microtubule
binding [goid 0008017; evidence TAS; pmid
8599929]; go_function: transcription factor
activity [goid 0003700; evidence TAS; pmid
8599929]; go_function: RNA binding [goid 0003723]
[evidence IEA]; go_process: mitosis [goid 0007067]
[evidence TAS; pmid 8599929]; go_process:
transcription from Pol II promoter [goid 0006366]
[evidence TAS; pmid 7745706]; go_process: mRNA
splicing [goid 0006371; evidence IEA];
go_process: regulation of transcription,
DNA-dependent [goid 0006355; evidence IEA];
go_process: nuclear mRNA splicing, via spliceosome
[goid 0000398; evidence IEA]; Homo sapiens TAR
DNA binding protein (TARDBP), mRNA.
Tumor necrosis factor receptor superfamily, member TNFRSF1B Hs.256278
1B
UBX domain containing 3 UBXD3 Hs.432503
GLC3C Calmodulin 1 (phosphorylase kinase, delta) CALM1 Hs.282410
Chromosome 14 open reading frame 141 LTBP2 Hs.512776
Chromosome 14 open reading frame 168 C14orf168 Hs.7086
Chromosome 14 open reading frame 168 C14orf168 Hs.7086
Chromosome 14 open reading frame 58 C14orf58 Hs.267566
Ceiodinase, iodothyronine, type II DIO2 Hs.436020
Hypothetical protein LOC283578 LOC283578 Hs.212992
KIAA0759 KIAA0759 Hs.7285
KIAA1737 KIAA1737 Hs.22452
Ribonuclease, RNase A family, 2 (liver, RNASE2 Hs.728
eosinophil-derived neurotoxin)
RNA-binding region (RNP1, RRM) containing 7 RBM25 Hs.197184
Serine palmitoyltransferase, long chain base SPTLC2 Hs.59403
subunit 2
Synonym: ACYPE; isoform a is encoded by transcript ACYP1
variant 1; go_function: acylphosphatase activity
[goid 0003998; evidence TAS; pmid 7796909];
go_function: hydrolase activity [goid 0016787]
[evidence IEA]; go_process: phosphate metabolism
[goid 0006796; evidence TAS; pmid 3026468]; Homo
sapiens acylphosphatase 1, erythrocyte (common)
type (ACYP1), transcript variant 1, mRNA.
15q11-13 7i87g09.x1 NCI_CGAP_Ov18 Homo sapiens cDNA clone SNRPN
IMAGE:3341728 3', mRNA sequence.
AV715153 DCB Homo sapiens cDNA clone DCBBNE07 5', UBR1
mRNA sequence.
CDNA FLJ37663 fis, clone BRHIP2011120 LOC283713 Hs.4986
Hypothetical protein FLJ20313 FLJ20313 Hs.126721
Hypothetical protein FLJ38426 FLJ38426 Hs.6799
Likely ortholog of mouse aquarius AQR Hs.129952
Oculocutaneous albinism II (pink-eye dilution OCA2 Hs.82027
homolog, mouse)
PRO1914 protein FLJ20582 Hs.5327
Protein inhibitor of activated STAT, 1 PIAS1 Hs.75251
Similar to RIKEN cDNA 5730421E18 gene MGC14798 Hs.149176
Small nuclear ribonucleoprotein polypeptide N SNRPN Hs.48375
Transient receptor potential cation channel, TRPM1 Hs.155942
subfamily M, member 1
Transmembrane 6 superfamily member 1 HDGFRP3 Hs.151155
Ubiquitin protein ligase E3A (human papilloma UBE3A Hs.180686
virus E6-associated protein, Angelman syndrome)
Xm51f06.x1 NCI_CGAP_GC6 Homo sapiens cDNA clone FLJ20582
IMAGE:2687747 3' similar to contains MER2.b2 MER2
repetitive element; mRNA sequence.
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