Table 7 of Liton, Mol Vis 2006; 12:774-790.


Table 7.

List of the known genes significantly downregulated in POAG trabecular meshwork (TM) tissue. Genes were present in all the control samples. The presence of (P), marginal (M), or absence of (A) a signal in each of the two POAG samples is indicated in the POAG TM column.

                                                         Fold               POAG
                Gene name                    Unigene    change   p value     TM
-----------------------------------------   ---------   ------   --------   ----
VPS10 domain receptor protein SORCS 3       SORCS3      9.021    0.0026     A
mitogen-activated protein kinase 6          MAP2K6      5.794    0.0108     P
cadherin 10, type 2 (T2-cadherin)           CDH10       5.041    0.00537    P,A
TPTE and PTEN homologous inositol lipid     TPTEps1     4.992    0.000971   A
phosphatase pseudogene
calbindin 1, 28 kDa                         CALB1       4.907    0.00917    P,M
leucine-rich, glioma inactivated 1          LGI1        3.976    0.00129    P
matrix metalloproteinase 10                 MMP10       3.97     0.0094     P
(stromelysin 2)
testis expressed sequence 15                TEX15       3.821    0.0317     A
WNT inhibitory factor 1                     WIF1        3.774    0.0151     P
carboxylesterase 1 (monocyte/macrophage     CES1        3.352    0.0417     P,A
serine esterase 1)
growth arrest-specific 7                    GAS7        3.186    0.0365     P,A
protein kinase, lysine deficient 4          PRKWNK4     3.117    0.0145     P
cytochrome P450, family 39, subfamily A,    CYP39A1     3.1      0.000473   P
polypeptide 1
glycoprotein hormone alpha 2                GPHA2       3.012    0.000588   P
ATP-binding cassette, sub-family A          ABCA9       2.822    0.00679    A
(ABC1), member 9
purinergic receptor P2Y, G-protein          P2RY12      2.684    0.0048     P,A
coupled, 12
nebulin                                     NEB         2.627    0.00939    P
cortactin binding protein 2                 CORTBP2     2.575    0.0111     P
proprotein convertase subtilisin/kexin      PCSK1N      2.575    0.0259     P
type 1 inhibitor
paraoxonase 3                               PON3        2.523    0.006      A
solute carrier family 10, member 4          SLC10A4     2.496    0.000439   P
cancer susceptibility candidate 1           CASC1       2.436    0.0188     P
solute carrier family 35, member D1         SLC35D1     2.296    0.00196    P
ceruloplasmin                               CP          2.282    0.00137    P
tripartite motif protein TRIM9 isoform      TRIM9       2.235    0.0246     P
alpha (TRIM9)
protocadherin beta 6                        PCDHB6      2.223    1.49E-05   P
cadherin-like 24                            CDH24       2.221    0.00234    A
low density lipoprotein-related protein     LRP1B       2.221    0.0183     P
1B (deleted in tumors)
solute carrier family 6 (neurotransmitter   SLC6A1      2.218    0.00295    P
transporter, GABA), member 1
frizzled homolog 10 (Drosophila)            FZD10       2.18     0.00155    P
H19, imprinted maternally expressed         H19         2.179    0.00277    P
untranslated mRNA
adrenergic, beta-2-, receptor, surface      ADRB2       2.157    0.00589    P
serine protease EOS                         EOS         2.146    0.00748    P,A
X transporter protein 3                     SLC6A20     2.115    0.00243    P
delta-notch-like EGF repeat-containing      DNER        2.11     0.011      P,M
transmembrane
protein phosphatase 1, regulatory           PPP1R1B     2.089    0.0198     P
(inhibitor) subunit 1B
B-cell CLL/lymphoma 6, member B (zinc       BCL6B       2.078    0.0495     P,M
finger protein)
iduronidase, alpha-L-                       IDUA        2.052    0.00162    A
GATA binding protein 6                      GATA6       2.04     0.0433     P
EGF-like-domain, multiple 6                 EGFL6       2.035    0.00526    P
SMA3                                        LOC153561   2.023    0.0141     P
EH-domain containing 3                      EHD3        2.015    0.0307     P,A
sortilin-related receptor, L(DLR class) A   SORL1       2.009    0.000666   P
repeats-containing
acyl-Coenzyme A dehydrogenase, long chain   ACADL       2.005    0.000153   A

Liton, Mol Vis 2006; 12:774-790 <http://www.molvis.org/molvis/v12/a87/>
©2006 Molecular Vision <http://www.molvis.org/molvis/>
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