Table 6 of
Liton, Mol Vis 2006;
12:774-790.
Table 6.
List of the known genes significantly upregulated in POAG trabecular meshwork (TM) tissue. Genes were present in all of the POAG samples. The presence of (P), marginal (M), or absence of (A) a signal in each of the three control samples is indicated in the Control TM column.
Fold Control Gene name Unigene change p value TM ----------------------------------------- --------- ------ -------- ------- selectin E (endothelial adhesion SELE 31.08 0.0258 A-A-A molecule 1) testes development-related NYD-SP21 NYD-SP21 12.67 0.00513 A-A-A ELOVL family member 7, elongation of long ELOVL7 6.864 0.00908 A-P-A chain fatty acid prokineticin 2 PROK2 6.778 0.00682 A-A-A BCL2-related protein A1 BCL2A1 6.431 0.0244 P-P-A SRY (sex determining region Y)-box 17 SOX17 4.236 0.0446 P-A-P neural precursor cell expressed, NEDD9 4.184 0.00521 P-P-P developmentally down-regulated 9 LIM domain only 7 LMO7 3.706 0.0201 P-P-P protocadherin 17 LOC144997 3.422 0.0481 P-P-A membrane protein, palmitoylated 3 (MAGUK MPP3 3.237 0.0173 M-M-P p55 subfamily member 3) solute carrier family 16 (monocarboxylic SLC16A6 3.016 0.0378 P-P-P acid transporters), member 6 transthyretin (prealbumin, TTR 2.945 0.00554 A-P-P amyloidosis type I) Microfibril-associated glycoprotein-2 MAGP2 2.849 0.00292 A-A-A hypoxia-inducible protein 2 HIG2 2.838 0.00298 P-P-P ecotropic viral integration site 1 EVI1 2.809 0.0195 P-P-A G protein-coupled receptor 146 GPR146 2.78 0.0376 P-P-P oxysterol binding protein-like 6 OSBPL6 2.777 0.00563 P-P-A haptoglobin HP 2.76 0.0145 P-P-P chemokine (C-X-C motif) ligand 6 CXCL6 2.713 0.000373 P-M-P (granulocyte chemotactic protein 2) immune associated nucleotide hIAN7 2.695 0.000109 P-P-P zinc finger protein 36, C3H type, ZFP36 2.686 0.0368 P-P-P homolog (mouse) synaptotagmin IV SYT4 2.635 0.0101 P-A-P lunatic fringe homolog (Drosophila) LFNG 2.621 0.0073 P-A-A regulator of G-protein signalling 1 RGS1 2.537 0.00191 P-P-P neuropeptide Y receptor Y2 NPY2R 2.535 0.0176 A-A-P v-fos FBJ murine osteosarcoma viral FOS 2.521 0.0134 P-P-A oncogene homolog transient receptor potential cation TRPM1 2.468 0.0315 P-P-P channel, subfamily M, member 1 matrix metalloproteinase 1 (interstitial MMP1 2.463 0.0393 P-A-A collagenase) neuropilin (NRP) and tolloid (TLL)-like 2 NETO2 2.416 0.0362 P-P-P Epstein-Barr virus induced gene 2 EBI2 2.41 0.00647 P-P-P adenosine A3 receptor ADORA3 2.393 0.0044 P-P-P interleukin 1 receptor, type II IL1R2 2.388 0.0233 P-A-A chemokine (C-C motif) ligand 15 CCL15 2.366 0.0107 P-P-P tripartite motif-containing 16 TRIM16 2.352 0.0215 P-M-P platelet activating receptor homolog H963 2.324 0.000568 P-P-A ribonuclease, RNase A family, k6 RNASE6 2.253 0.00015 P-M-A membrane-spanning 4-domains, subfamily A, MS4A7 2.227 0.00326 P-P-P member 7 protein tyrosine phosphatase, PTPN4 2.175 0.0222 P-A-P non-receptor type 4 (megakaryocyte) Bruton agammaglobulinemia tyrosine kinase BTK 2.159 0.000247 P-A-A myelin basic protein MBP 2.149 0.0183 P-P-A chloride intracellular channel 2 CLIC2 2.148 0.0377 P-P-P Fc fragment of IgG, high affinity Ia, FCGR1A 2.142 0.00185 P-P-P receptor for (CD64) F-box only protein 4 FBXO4 2.116 0.0061 P-P-P cadherin 19, type 2 CDH19 2.055 0.00322 P-P-P carbohydrate (chondroitin 4) CHST12 2.05 0.0221 P-M-P sulfotransferase 12 CD1D antigen, d polypeptide CD1D 2.044 0.00277 P-P-P delta sleep inducing peptide, DSIPI 2.038 0.00392 P-P-P immunoreactor insulin-like growth factor 2 IGF2 2.018 0.0051 P-P-P (somatomedin A) |