Table 6 of Liton, Mol Vis 2006; 12:774-790.


Table 6.

List of the known genes significantly upregulated in POAG trabecular meshwork (TM) tissue. Genes were present in all of the POAG samples. The presence of (P), marginal (M), or absence of (A) a signal in each of the three control samples is indicated in the Control TM column.

                                                         Fold               Control
                Gene name                    Unigene    change   p value      TM
-----------------------------------------   ---------   ------   --------   -------
selectin E (endothelial adhesion            SELE        31.08    0.0258      A-A-A
molecule 1)
testes development-related NYD-SP21         NYD-SP21    12.67    0.00513     A-A-A
ELOVL family member 7, elongation of long   ELOVL7      6.864    0.00908     A-P-A
chain fatty acid
prokineticin 2                              PROK2       6.778    0.00682     A-A-A
BCL2-related protein A1                     BCL2A1      6.431    0.0244      P-P-A
SRY (sex determining region Y)-box 17       SOX17       4.236    0.0446      P-A-P
neural precursor cell expressed,            NEDD9       4.184    0.00521     P-P-P
developmentally down-regulated 9
LIM domain only 7                           LMO7        3.706    0.0201      P-P-P
protocadherin 17                            LOC144997   3.422    0.0481      P-P-A
membrane protein, palmitoylated 3 (MAGUK    MPP3        3.237    0.0173      M-M-P
p55 subfamily member 3)
solute carrier family 16 (monocarboxylic    SLC16A6     3.016    0.0378      P-P-P
acid transporters), member 6
transthyretin (prealbumin,                  TTR         2.945    0.00554     A-P-P
amyloidosis type I)
Microfibril-associated glycoprotein-2       MAGP2       2.849    0.00292     A-A-A
hypoxia-inducible protein 2                 HIG2        2.838    0.00298     P-P-P
ecotropic viral integration site 1          EVI1        2.809    0.0195      P-P-A
G protein-coupled receptor 146              GPR146      2.78     0.0376      P-P-P
oxysterol binding protein-like 6            OSBPL6      2.777    0.00563     P-P-A
haptoglobin                                 HP          2.76     0.0145      P-P-P
chemokine (C-X-C motif) ligand 6            CXCL6       2.713    0.000373    P-M-P
(granulocyte chemotactic protein 2)
immune associated nucleotide                hIAN7       2.695    0.000109    P-P-P
zinc finger protein 36, C3H type,           ZFP36       2.686    0.0368      P-P-P
homolog (mouse)
synaptotagmin IV                            SYT4        2.635    0.0101      P-A-P
lunatic fringe homolog (Drosophila)         LFNG        2.621    0.0073      P-A-A
regulator of G-protein signalling 1         RGS1        2.537    0.00191     P-P-P
neuropeptide Y receptor Y2                  NPY2R       2.535    0.0176      A-A-P
v-fos FBJ murine osteosarcoma viral         FOS         2.521    0.0134      P-P-A
oncogene homolog
transient receptor potential cation         TRPM1       2.468    0.0315      P-P-P
channel, subfamily M, member 1
matrix metalloproteinase 1 (interstitial    MMP1        2.463    0.0393      P-A-A
collagenase)
neuropilin (NRP) and tolloid (TLL)-like 2   NETO2       2.416    0.0362      P-P-P
Epstein-Barr virus induced gene 2           EBI2        2.41     0.00647     P-P-P
adenosine A3 receptor                       ADORA3      2.393    0.0044      P-P-P
interleukin 1 receptor, type II             IL1R2       2.388    0.0233      P-A-A
chemokine (C-C motif) ligand 15             CCL15       2.366    0.0107      P-P-P
tripartite motif-containing 16              TRIM16      2.352    0.0215      P-M-P
platelet activating receptor homolog        H963        2.324    0.000568    P-P-A
ribonuclease, RNase A family, k6            RNASE6      2.253    0.00015     P-M-A
membrane-spanning 4-domains, subfamily A,   MS4A7       2.227    0.00326     P-P-P
member 7
protein tyrosine phosphatase,               PTPN4       2.175    0.0222      P-A-P
non-receptor type 4 (megakaryocyte)
Bruton agammaglobulinemia tyrosine kinase   BTK         2.159    0.000247    P-A-A
myelin basic protein                        MBP         2.149    0.0183      P-P-A
chloride intracellular channel 2            CLIC2       2.148    0.0377      P-P-P
Fc fragment of IgG, high affinity Ia,       FCGR1A      2.142    0.00185     P-P-P
receptor for (CD64)
F-box only protein 4                        FBXO4       2.116    0.0061      P-P-P
cadherin 19, type 2                         CDH19       2.055    0.00322     P-P-P
carbohydrate (chondroitin 4)                CHST12      2.05     0.0221      P-M-P
sulfotransferase 12
CD1D antigen, d polypeptide                 CD1D        2.044    0.00277     P-P-P
delta sleep inducing peptide,               DSIPI       2.038    0.00392     P-P-P
immunoreactor
insulin-like growth factor 2                IGF2        2.018    0.0051      P-P-P
(somatomedin A)

Liton, Mol Vis 2006; 12:774-790 <http://www.molvis.org/molvis/v12/a87/>
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