Table 3 of
Liton, Mol Vis 2006;
12:774-790.
Table 3.
Summary of 25 genes sharing the highest signal values in both normal native tissue and cultured human trabecular meshwork (HTM) cells. The Unigene site is provided in the public domain by the National Center for Biotechnology Information, Bethesda, MD. The asterisk indicates that transcripts are represented and the double asterisk indicates that the transcripts are highly represented in the libraries from postmortem trabecular meshwork (TM), perfused TM, infant primary TM culture, and from gene expression profile of cultured HTM using the U95Av2 Affymetrix microarrays (12,626 probe sets). The term SV indicates signal value.
TM-Tissue TM-Cells Gene name Unigene (SV±SD) (SV±SD) [9] [8] [11] [12] --------------------- ------- -------------- --------------- --- --- ---- ---- Beta actin ACTB 29338.7±4900.8 45504.0±13031.0 * * * ** Calreticulin MNT 27317.0±7448.7 32472.2±27730.8 * * Matrix Gla protein MGP 26948.0±6100.0 30903.3±13352.6 ** ** * * Tumor protein, TPT1 25270.3±5290.6 33857.7±7219.6 ** ** * translationally controlled 1 Heterogeneous nuclear HNRPA1 24886.7±4085.1 30312.0±11590.7 * * ribonucleoprotein A1 Chitinase 3-like 1 CHI3L1 24598.3±4220.7 39115.3±13522.0 * ** ** Heterogeneous nuclear HNRPH1 24576.3±3208.4 20595.0±12332.5 * * ribonucleoprotein H1 Calponin 3, acidic CNN3 22844.0±3750.4 21742.0±16406.3 * * Metastasis-associated MALAT1 22386.0±1582.3 21798.3±15656.1 lung adenocarcinoma transcript 1 Amyloid beta (A4) APP 22323.0±7007.3 21240.7±15793.5 ** * precursor protein H3 histone, H3F3A 21357.3±2846.2 26101.3±11870.1 * * * family 3A Nuclear ubiquitous NUCKS 21013.0±4169.4 20936.3±13559.1 * casein kinase/ cyclin-dependent kinase substrate Tissue inhibitor of TIMP2 20966.3±2314.1 28300.0±8642.6 * * metalloproteinase 2 Heat shock 90 kDa HSPCA 20751.3±6126.9 25471.3±9332.5 * * * protein 1, alpha Heterogeneous nuclear HNRPK 20493.7±3298.0 21150.7±8755.2 * * ribonucleoprotein K ATP synthase, H+ ATP5E 20445.7±3525.3 28864.0±15308.5 * transporting, mitochondrial F1 complex, epsilon subunit ATPase, H+ ATP6V0E 20388.7±1447.9 19010.2±15830.0 * * transporting, lysosomal 9 kDa, V0 subunit e Mortality factor 4 MORF4L2 20365.3±6236.3 25724.7±9497.2 like 2 SMT3 suppressor of SUMO2 20276.3±4859.2 24991.3±13212.0 * * mif two 3 homolog 2 (yeast) CD59 antigen p18-20 CD59 20138.7±2108.3 19595.7±6500.0 * * * High-mobility group HMGN2 19939.7±4243.4 19998.3±9536.1 * * nucleosomal binding domain 2 Interferon induced IFITM3 19864.7±331.9 22892.0±2719.0 * ** transmembrane protein 3 (1-8U) Tyrosine YWHAE 19845.7±2765.7 21488.7±11620.9 * * 3-monooxygenase/ tryptophan 5-monooxygenase activation protein Transmembrane 4 TM4SF1 19822.7±1445.5 24529.0±10827.0 * * * * superfamily member 1 Calnexin CANX 19817.0±2297.7 21184.0±10323.6 * * * |