Table 3 of Liton, Mol Vis 2006; 12:774-790.


Table 3.

Summary of 25 genes sharing the highest signal values in both normal native tissue and cultured human trabecular meshwork (HTM) cells. The Unigene site is provided in the public domain by the National Center for Biotechnology Information, Bethesda, MD. The asterisk indicates that transcripts are represented and the double asterisk indicates that the transcripts are highly represented in the libraries from postmortem trabecular meshwork (TM), perfused TM, infant primary TM culture, and from gene expression profile of cultured HTM using the U95Av2 Affymetrix microarrays (12,626 probe sets). The term SV indicates signal value.

                                    TM-Tissue         TM-Cells
      Gene name         Unigene      (SV±SD)           (SV±SD)       [9]   [8]   [11]   [12]
---------------------   -------   --------------   ---------------   ---   ---   ----   ----
Beta actin              ACTB      29338.7±4900.8   45504.0±13031.0   *     *     *      **
Calreticulin            MNT       27317.0±7448.7   32472.2±27730.8   *                  *
Matrix Gla protein      MGP       26948.0±6100.0   30903.3±13352.6   **    **    *      *
Tumor protein,          TPT1      25270.3±5290.6   33857.7±7219.6    **          **     *
translationally
controlled 1
Heterogeneous nuclear   HNRPA1    24886.7±4085.1   30312.0±11590.7   *                  *
ribonucleoprotein A1
Chitinase 3-like 1      CHI3L1    24598.3±4220.7   39115.3±13522.0   *     **           **
Heterogeneous nuclear   HNRPH1    24576.3±3208.4   20595.0±12332.5   *                  *
ribonucleoprotein H1
Calponin 3, acidic      CNN3      22844.0±3750.4   21742.0±16406.3   *                  *
Metastasis-associated   MALAT1    22386.0±1582.3   21798.3±15656.1
lung adenocarcinoma
transcript 1
Amyloid beta (A4)       APP       22323.0±7007.3   21240.7±15793.5               **     *
precursor protein
H3 histone,             H3F3A     21357.3±2846.2   26101.3±11870.1         *     *      *
family 3A
Nuclear ubiquitous      NUCKS     21013.0±4169.4   20936.3±13559.1   *
casein kinase/
cyclin-dependent
kinase substrate
Tissue inhibitor of     TIMP2     20966.3±2314.1   28300.0±8642.6    *                  *
metalloproteinase 2
Heat shock 90 kDa       HSPCA     20751.3±6126.9   25471.3±9332.5    *           *      *
protein 1, alpha
Heterogeneous nuclear   HNRPK     20493.7±3298.0   21150.7±8755.2    *                  *
ribonucleoprotein K
ATP synthase, H+        ATP5E     20445.7±3525.3   28864.0±15308.5   *
transporting,
mitochondrial F1
complex, epsilon
subunit
ATPase, H+              ATP6V0E   20388.7±1447.9   19010.2±15830.0   *                  *
transporting,
lysosomal 9 kDa, V0
subunit e
Mortality factor 4      MORF4L2   20365.3±6236.3   25724.7±9497.2
like 2
SMT3 suppressor of      SUMO2     20276.3±4859.2   24991.3±13212.0   *                  *
mif two 3 homolog 2
(yeast)
CD59 antigen p18-20     CD59      20138.7±2108.3   19595.7±6500.0    *           *      *
High-mobility group     HMGN2     19939.7±4243.4   19998.3±9536.1    *                  *
nucleosomal binding
domain 2
Interferon induced      IFITM3    19864.7±331.9    22892.0±2719.0          *            **
transmembrane protein
3 (1-8U)
Tyrosine                YWHAE     19845.7±2765.7   21488.7±11620.9   *                  *
3-monooxygenase/
tryptophan
5-monooxygenase
activation protein
Transmembrane 4         TM4SF1    19822.7±1445.5   24529.0±10827.0   *     *     *      *
superfamily member 1
Calnexin                CANX      19817.0±2297.7   21184.0±10323.6   *           *      *

Liton, Mol Vis 2006; 12:774-790 <http://www.molvis.org/molvis/v12/a87/>
©2006 Molecular Vision <http://www.molvis.org/molvis/>
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