Table 3 of Metlapally, Mol Vis 2006; 12:725-734.


Table 3.

Potential integrin receptors present in the mammalian sclera. Given the known association of individual integrin subunits and the subunits expressed in the sclera, the integrin receptors have been listed. Also included are the preferred ligands of the individual receptors and whether those ligands have been identified in the sclera. The presence of the α1/β1- and α2/β1-integrin receptors has previously been reported in vivo [31].

                          Evidence for
                           ligands in
Receptors     Ligands      the sclera
---------   -----------   ------------
  α1/β1     collagens      [49,68,69]
            laminins

  α2/β1     collagens      [49,68,69]
            laminins

  α3/β1     collagens      [49,67,69]
            laminins
            fibronectin

  α4/β1     fibronectin    [67]

  α5/β1     fibronectin    [67]

  α6/β1     laminins       [68,69]

  α6/β4     laminins       [68,69]

  α9/β1     tenascin       [70]

 α10/β1     collagens      [49]

 α11/β1     collagens      [49]

  αv/β1     fibronectin    [67,71]
            vitronectin

  αv/β5     fibronectin    [67,71]
            vitronectin

  αv/β8     collagens      [49,67,69]
            laminins
            fibronectin

Metlapally, Mol Vis 2006; 12:725-734 <http://www.molvis.org/molvis/v12/a81/>
©2006 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535