Table 4 of
Inagaki, Mol Vis 2006;
12:673-680.Table 4 of
Inagaki, Mol Vis 2006;
12:673-680.
Table 4.
Clinical characteristics of glaucoma patients according to genotype for Arg16Gly in the ADRB2 gene. Differences in the dominant model of polymorphisms of ADRB2/Arg16Gly in association with three clinical characteristics are shown. Associations between clinical characteristics (age, IOP, and visual field score at diagnosis) and genotypes were assessed by multivariate analyses carried out with a logistic regression model. For the Arg16Gly polymorphism in the ADRB2 gene in POAG patients, patients in the Arg/Gly+Gly/Gly group were significantly younger at diagnosis than patients in the Arg/Arg group (56.7±11.7 years versus 62.9±12.7, p<0.001). P values were calculated with logistic regression analysis. The asterisk indicates a p<0.05.
Genotype
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Phenotype Clinical characteristics Arg/Arg Arg/Gly+Gly/Gly p value
--------- ------------------------------- ----------------- ------------------- -------
OAG Age at diagnosis (years) 57.9±12.7 (n=100) 56.3±12.7 (n=371) 0.085
IOP at diagnosis (mm Hg) 20.3± 5.8 (n=90) 20.8± 6.5 (n=335) 0.469
Visual field score at diagnosis 2.8± 0.7 (n=99) 2.9± 0.8 (n=375) 0.508
POAG Age at diagnosis (years) 62.9±12.7 (n=39) 56.7±11.7 (n=162) <0.001*
IOP at diagnosis (mm Hg) 26.3± 4.9 (n=33) 26.3± 6.0 (n=147) 0.973
Visual field score at diagnosis 3.0± 0.9 (n=38) 3.1± 0.9 (n=164) 0.898
NTG Age at diagnosis (years) 54.7±11.7 (n=61) 56.0±13.5 (n=209) 0.531
IOP at diagnosis (mm Hg) 16.8± 2.5 (n=57) 16.6± 2.4 (n=188) 0.581
Visual field score at diagnosis 2.7± 0.5 (n=61) 2.8± 0.7 (n=211) 0.266
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