Table 1 of Yao, Mol Vis 2006; 12:649-654.


Table 1. Haplotype and compound genotype frequencies of the single nucleotide polymorphisms (SNPs) at IVS8 +4 and +32

The significance for comparing normal tension glaucoma (NTG) participants with controls and for comparing POAG/IOP participants with controls are shown under the headings p (NTG) and p (POAG), respectively. For multiple comparisons, the significance p values are at the level of 0.017 for three comparisons and 0.013 for four comparisons. The asterisk indicates that Fisher's exact test was applied due to small sample size.

    Haplotype
------------------      NTG      POAG/IOP    Controls      p       p
IVS8 +4   IVS8 +32     n (%)       n (%)       n (%)     (NTG)   (POAG)
-------   --------   ---------   ---------   ---------   -----   ------
   C         T       55 (45.1)   55 (57.3)   56 (58.3)   0.05    0.88
   C         C       64 (52.5)   40 (41.7)   38 (39.6)   0.06    0.77
   T         T        3  (2.4)    1  (1.0)    2  (2.1)   1.00*   1.00*
Combined comparison: p(NTG)=0.15, df=2; p(POAG)=0.82, df=2

Compound genotype
------------------      NTG      POAG/IOP    Controls      p       p
IVS8 +4   IVS8 +32     n (%)       n (%)       n (%)     (NTG)   (POAG)
-------   --------   ---------   ---------   ---------   -----   ------
  CC         TT      11 (18.0)   19 (39.6)   14 (29.2)   0.16    0.28
  CC         TC      30 (49.2)   16 (33.3)   26 (54.2)   0.61    0.04
  CC         CC      17 (27.9)   12 (25.0)    6 (12.5)   0.05    0.12
  CT         TT       3  (4.9)    1  (2.1)    2  (4.2)   1.00*   1.00*
Combined comparison: p(NTG)=0.32, df=3; p(POAG)=0.14, df=3

Yao, Mol Vis 2006; 12:649-654 <http://www.molvis.org/molvis/v12/a73/>
©2006 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535