Table 1 of
Yao, Mol Vis 2006;
12:649-654.
Table 1. Haplotype and compound genotype frequencies of the single nucleotide polymorphisms (SNPs) at IVS8 +4 and +32
The significance for comparing normal tension glaucoma (NTG) participants with controls and for comparing POAG/IOP participants with controls are shown under the headings p (NTG) and p (POAG), respectively. For multiple comparisons, the significance p values are at the level of 0.017 for three comparisons and 0.013 for four comparisons. The asterisk indicates that Fisher's exact test was applied due to small sample size.
Haplotype ------------------ NTG POAG/IOP Controls p p IVS8 +4 IVS8 +32 n (%) n (%) n (%) (NTG) (POAG) ------- -------- --------- --------- --------- ----- ------ C T 55 (45.1) 55 (57.3) 56 (58.3) 0.05 0.88 C C 64 (52.5) 40 (41.7) 38 (39.6) 0.06 0.77 T T 3 (2.4) 1 (1.0) 2 (2.1) 1.00* 1.00* Combined comparison: p(NTG)=0.15, df=2; p(POAG)=0.82, df=2 Compound genotype ------------------ NTG POAG/IOP Controls p p IVS8 +4 IVS8 +32 n (%) n (%) n (%) (NTG) (POAG) ------- -------- --------- --------- --------- ----- ------ CC TT 11 (18.0) 19 (39.6) 14 (29.2) 0.16 0.28 CC TC 30 (49.2) 16 (33.3) 26 (54.2) 0.61 0.04 CC CC 17 (27.9) 12 (25.0) 6 (12.5) 0.05 0.12 CT TT 3 (4.9) 1 (2.1) 2 (4.2) 1.00* 1.00* Combined comparison: p(NTG)=0.32, df=3; p(POAG)=0.14, df=3 |