Table 8 of Lutty, Mol Vis 2006; 12:532-580.


Table 8. Nine month structural outcome for randomized patients

The analysis was based on the structural outcome of these eyes observed by the examining ophthalmologist at the 9 month examination and each was classified as favorable or unfavorable (UF). Twenty-four eyes with partial retinal detachment not including the macula (stage 4A) had vitrectomy or a scleral buckle procedure prior to the 9 month examination and are included in this table as having an UF outcome. Stage 4B or 5 eyes were considered UF in this study a priori. There were 292 patients with bilateral ROP and 43 with asymmetric ROP. The structural outcome could not be determined for five of the bilateral eyes, and one of those with asymmetric ROP. The χ2 test (χ-sq) for the infants with bilateral ROP was based on discordant pairs (25 infants had an eye treated early with a favorable outcome and an eye managed conventionally with an UF outcome; 6 infants had an eye treated early with a UF outcome and an eye managed conventionally with a favorable outcome), and showed a significantly improved outcome for the early treated eyes (p<0.001).

Republished with permission of the American Medical Association from Early Treatment For Retinopathy Of Prematurity Cooperative Group. Revised indications for the treatment of retinopathy of prematurity: results of the early treatment for retinopathy of prematurity randomized trial. Arch Ophthalmol 2003; 121:1684-94. Copyright ©2003 American Medical Association. All rights reserved.

              Eyes treated
              at high-risk    Conventionally
              prethreshold     managed eyes
             --------------   --------------
               N      % UF      N      % UF    χ-sq       p
             -----   ------   -----   ------   -----   -------
Bilateral     289     10.4     290     17.2    11.7    <0.001
Asymmetric     42      0.0      36      2.8     1.2     0.28
             -----   ------   -----   ------   -----   -------
Total         331      9.1     326     15.6    12.6    <0.001

Lutty, Mol Vis 2006; 12:532-580 <http://www.molvis.org/molvis/v12/a63/>
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