Figure 3. Strain-dependent corneal angiogenesis

A: Corneas were photographed 7 days after implantation of a hydron polymer pellet containing 75 ng of basic fibroblast growth factor (bFGF) into a central corneal micropocket. B: Resting limbal vascularity was strain dependent. Photographs of the limbal vessels were taken in normal, unoperated, adult eyes. C: Limbal vessel density differences between mouse strains were further evaluated by fluorescence microscopy after labeling with endothelial-specific fluorescein conjugated Griffonia simplicifolia lectin.

Republished with permission of The Association for Research in Vision & Ophthalmology from Chan CK, Pham LN, Chinn C, Spee C, Ryan SJ, Akhurst RJ, Hinton DR. Mouse strain-dependent heterogeneity of resting limbal vasculature. Invest Ophthalmol Vis Sci 2004; 45:441-7.