Table 2 of
John-Aryankalayil, Mol Vis 2006;
12:55-64.Table 2 of
John-Aryankalayil, Mol Vis 2006;
12:55-64.
Table 2. Microarray analysis of human pterygium and normal autologous conjunctiva
The table lists the Affymetric probe set name, the Genbank accession number, the fold change in gene expression in human pterygium relative to normal autologous conjunctiva by microarray analysis, and a brief description of the name or major function of the gene product. The genes shown are statistically significant with p<0.05.
Genbank
Affymetric accession Fold
name number change Name Description
---------- --------- ------ ---------------------- -----------------------------------------------
Increased expression in pterygium
311_s_at X02761 8.5 Fibronectin cell adhesion and migration
34290_f_at AA995126 5.0 TRAP100 thyroid hormone receptor-associated protein
32128_at Y13710 4.9 MIP-4 chemokine; pro-inflammatory
32488_at X14420 4.1 collagen III cell adhesion and migration
34778_at AA418080 3.8 leucine rich repeat integral to membrane
38634_at M11433 3.6 RBP1 ligand trafficking; muscle malignancy
38111_at X15998 3.3 versican, V1 matrix expansion in arterial and smooth muscle
cells
37600_at U68186 3.2 ECM 1 extracellular matrix protein 1
34015_at AF004021 3.2 prostaglandin receptor role in smooth muscle contraction
32582_at AF001548 3.1 myosin heavy chain 11 smooth muscle component
40500_at AF007138 3.1 NDRG4 response to stress and cell differentiation
34665_g_at X62573 2.9 receptor for CD32 signal transduction, cell growth and
maintenance
38351_at AL050154 2.8 mRNA; clone from clone DKFZp586L0120
37629_at M55268 2.5 casein kinase 2 phosphorylation and signal transduction
39710_at U30521 2.5 C5orf13 chromosome 5 open reading frame 13
607_s_at M10321 2.5 von Willebrand factor platelet/cell adhesion, binds to collagen III
32523_at M20470 2.4 clathrin protein binding; membrane trafficking
31610_at U21049 2.4 MAP 17 extracellular integral to membrane
32821_at A1762213 2.4 lipocalin 2 oncogene 24p3; transporter activity
41362_at X91249 2.3 ABCG1 cholesterol and phospholipid transport
34757_at AA595596 2.3 ADPRTL2 ribosyltransferase activity
38327_at M77348 2.2 SILV maturation of melanosomes
41471_at W72424 2.2 calgranulin B inflammatory response; cell-cell signaling
37269_at D38496 2.2 LZTR1 leucine-zipper-like transcriptional regulator 1
479_at U53446 2.1 DAB2 cell proliferation, signal transduction
38077_at X52022 2.1 collagen type VI cell adhesion and muscle development
37398_at AA100961 2.1 CD31 antigen (PECAM1) endothelial cell adhesion, signal transduction
33371_s_at NM_006868 2.0 RAB31 member of RAS oncogene family
40161_at L32137 2.0 COMP cartilage oligomeric matrix protein
Decreased expression in pterygium
40013_at BC022305 -2.0 CLIC2 chloride intracellular channel 2
36829_at AF022991 -2.0 Per1 circadian pacemaker protein
40425_at NM004428 -2.0 ephrin-A1 ligand for EPH group of receptor tyrosine
kinases
33373_at AL049951 -2.0 FUBP binds RNA; may function in control of splicing
37624_at M29458 -2.0 carbonic anhydrase family members are highly tissue-specific
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