Table 2 of
John-Aryankalayil, Mol Vis 2006;
12:55-64.
Table 2. Microarray analysis of human pterygium and normal autologous conjunctiva
The table lists the Affymetric probe set name, the Genbank accession number, the fold change in gene expression in human pterygium relative to normal autologous conjunctiva by microarray analysis, and a brief description of the name or major function of the gene product. The genes shown are statistically significant with p<0.05.
Genbank Affymetric accession Fold name number change Name Description ---------- --------- ------ ---------------------- ----------------------------------------------- Increased expression in pterygium 311_s_at X02761 8.5 Fibronectin cell adhesion and migration 34290_f_at AA995126 5.0 TRAP100 thyroid hormone receptor-associated protein 32128_at Y13710 4.9 MIP-4 chemokine; pro-inflammatory 32488_at X14420 4.1 collagen III cell adhesion and migration 34778_at AA418080 3.8 leucine rich repeat integral to membrane 38634_at M11433 3.6 RBP1 ligand trafficking; muscle malignancy 38111_at X15998 3.3 versican, V1 matrix expansion in arterial and smooth muscle cells 37600_at U68186 3.2 ECM 1 extracellular matrix protein 1 34015_at AF004021 3.2 prostaglandin receptor role in smooth muscle contraction 32582_at AF001548 3.1 myosin heavy chain 11 smooth muscle component 40500_at AF007138 3.1 NDRG4 response to stress and cell differentiation 34665_g_at X62573 2.9 receptor for CD32 signal transduction, cell growth and maintenance 38351_at AL050154 2.8 mRNA; clone from clone DKFZp586L0120 37629_at M55268 2.5 casein kinase 2 phosphorylation and signal transduction 39710_at U30521 2.5 C5orf13 chromosome 5 open reading frame 13 607_s_at M10321 2.5 von Willebrand factor platelet/cell adhesion, binds to collagen III 32523_at M20470 2.4 clathrin protein binding; membrane trafficking 31610_at U21049 2.4 MAP 17 extracellular integral to membrane 32821_at A1762213 2.4 lipocalin 2 oncogene 24p3; transporter activity 41362_at X91249 2.3 ABCG1 cholesterol and phospholipid transport 34757_at AA595596 2.3 ADPRTL2 ribosyltransferase activity 38327_at M77348 2.2 SILV maturation of melanosomes 41471_at W72424 2.2 calgranulin B inflammatory response; cell-cell signaling 37269_at D38496 2.2 LZTR1 leucine-zipper-like transcriptional regulator 1 479_at U53446 2.1 DAB2 cell proliferation, signal transduction 38077_at X52022 2.1 collagen type VI cell adhesion and muscle development 37398_at AA100961 2.1 CD31 antigen (PECAM1) endothelial cell adhesion, signal transduction 33371_s_at NM_006868 2.0 RAB31 member of RAS oncogene family 40161_at L32137 2.0 COMP cartilage oligomeric matrix protein Decreased expression in pterygium 40013_at BC022305 -2.0 CLIC2 chloride intracellular channel 2 36829_at AF022991 -2.0 Per1 circadian pacemaker protein 40425_at NM004428 -2.0 ephrin-A1 ligand for EPH group of receptor tyrosine kinases 33373_at AL049951 -2.0 FUBP binds RNA; may function in control of splicing 37624_at M29458 -2.0 carbonic anhydrase family members are highly tissue-specific |