Table 5 of
Medvedovic, Mol Vis 2006;
12:422-440.Table 5 of
Medvedovic, Mol Vis 2006;
12:422-440.
Table 5.
Gene Ontology (GO) categories of the gene cluster displaying a strong uniform increase in relative mRNA levels of regenerating lens compared to intact control lens.
Number
of genes False
in the discovery
Main GO category category Gene category rate
------------------ -------- -------------------------------------------- ---------
Biological Process 17 Response to biotic stimulus 1.0E-06
16 Defense response 1.2E-06
14 Immune response 3.3E-06
7 Humoral immune response 3.3E-06
10 Response to pest/pathogen/parasite 2.4E-05
18 Response to external stimulus 3.9E-04
4 Complement activation 1.6E-03
11 Cell adhesion 2.1E-03
4 Humoral defense mechanism (sensu Vertebrata) 2.3E-03
3 Antigen processing 3.3E-03
11 Response to stress 4.7E-03
3 Antigen presentation 5.1E-03
3 Complement activation, classical pathway 5.1E-03
4 Angiogenesis 6.2E-03
4 Blood vessel development 1.0E-02
2 Antigen presentation, exogenous antigen 1.2E-02
2 Antigen processing, exogenous antigen via 1.2E-02
MHC class II
2 Cell wall catabolism 1.6E-02
2 Regulation of angiogenesis 3.0E-02
2 Cytolysis 4.9E-02
Cellular Component 45 Extracellular 4.7E-11
41 Extracellular space 2.0E-10
13 Extracellular matrix 1.1E-06
2 Complement component C1q complex 1.9E-03
Molecular Function 10 Glycosaminoglycan binding 7.9E-10
9 Heparin binding 5.7E-09
4 Complement activity 4.3E-04
9 Cell adhesion molecule activity 1.9E-03
6 Defense/immunity protein activity 1.9E-03
2 Lysozyme activity 4.2E-03
3 Scavenger receptor activity 9.5E-03
2 MHC class II receptor activity 1.0E-02
5 Endopeptidase inhibitor activity 1.2E-02
5 Protease inhibitor activity 1.2E-02
6 Enzyme inhibitor activity 1.9E-02
10 Enzyme regulator activity 1.9E-02
2 Integrin binding 4.1E-02
2 Insulin-like growth factor binding 6.7E-02
2 Antimicrobial peptide activity 6.7E-02
24 Signal transducer activity 6.7E-02
|