Table 1 of
Medvedovic, Mol Vis 2006;
12:422-440.Table 1 of
Medvedovic, Mol Vis 2006;
12:422-440.
Table 1.
Top 50 genes with the greatest increase in relative mRNA expression levels of regenerating lens compared to intact control lens 1, 2, and 3 weeks post-extracapsular surgery. For a better visual presentation of the regulated genes at 1, 2, and 3 weeks, the times that each gene is highest is marked in red.
Fold changes
GenBank Average ------------------------
accession Gene name expression Week 1 Week 2 Week 3
--------- ---------------------------------------- ---------- ------ ------ ------
J05605 Thrombospondin 1 precursor 45 1.45 15.23 3.24
X81627 Neutrophil gelatinase-associated 141 4.26 5.27 6.93
lipocalin precursor
X51547 P lysozyme structural 3781 3.39 6.76 3.43
M33960 Serine (or cysteine) 436 5.49 4.13 3.46
proteinase inhibitor
AF071068 Dopa decarboxylase 1379 2.92 6.17 3.16
BC002069 Lysozyme 14018 3.63 5.29 3.12
AK018742 Procollagen, type VIII, alpha 1 481 1.55 7.62 2.75
M26498 Endothelin-2 precursor 1809 5.69 2.26 2.56
AK048616 Similar To Cdna Flj10680 40 1.02 8.41 1.01
BC013651 Serine (or cysteine) proteinase 3583 3.96 2.44 3.54
inhibitor, clade A, member 3N
D90343 Tenascin C 351 5.24 2.11 1.93
AK003674 Collagen triple helix repeat 2832 4.92 2.4 1.8
containing 1
BC006783 Connective tissue growth factor 3595 2.64 3.9 2.51
U49430 Ceruloplasmin 968 2.32 4.01 2.39
M17243 Tissue inhibitor of metalloproteinase 1 888 3.27 2.62 2.75
AJ223208 Cathepsin S 910 2.59 3.24 2.62
BC030071 Calcitonin/calcitonin-related 128 2.33 2.89 3.05
polypeptide, alpha
X97650 Myosin IF 1796 3.37 2.49 2.32
BC016551 Macrophage scavenger receptor 2 330 1.83 3.29 2.83
AF077829 TYRO protein tyrosine kinase 937 1.88 3.61 2.4
binding protein
AF213458 Cytochrome P450 4F 18 356 2.54 2.65 2.68
AF213458 Triggering receptor expressed on 745 1.67 3.42 2.75
myeloid cells 2b
L04264 Protein-lysine 6-oxidase precursor 3220 4.57 1.69 1.51
AF061272 C-type lectin 303 2.22 3.42 2.08
X58861 Complement component 1, q 1652 1.73 3.56 2.38
X60929 Low affinity Ig gamma Fc region 398 2.28 3.02 2.34
rec. III pre.
M73490 Apolipoprotein E 3890 1.63 3.83 2.15
BC027425 Membrane-spanning 4-domains 907 3.53 2.43 1.57
BC021539 Allograft inflammatory factor 1 557 3.01 2.75 1.74
AK010252 Leucine-rich repeat-containing 2 553 2.96 2.27 2.24
U47327 Histocompatibility 2 104 1.15 3.76 2.52
AF175282 Disintegrin-like and metalloprotease 431 2.65 2.69 1.93
with thrombospondin
U05264 Glycoprotein 49 B 1722 2.31 2.55 2.37
AF290914 Stabilin 1 547 2.68 2.85 1.69
X92959 Complement C1Q subcomponent 3207 2.24 2.76 2.2
D13664 Osteoblast specific factor 2 1752 3.61 1.87 1.71
X93035 Chitinase 3-like 1 6450 1.89 3 2.27
AK004165 Regulator of G-protein signaling 5 148 1.66 3.79 1.69
U42327 Vascular cell adhesion 1972 2.63 2.02 2.44
protein 1 precursor
M18524 H-2 class I histocompatibility antigen 328 1.43 3.16 2.47
AK018713 Cytochrome b-245 699 1.57 2.9 2.57
M69069 Histocompatibility 2, D region locus 1 301 1.11 3.63 2.28
AK014036 Brca1 interacting protein 48 1.11 4.31 1.54
M64866 Thrombospondin 2 2412 3.79 1.34 1.75
AK033376 Similar to Acetyl-Coa Synthetase 114 1.41 3.61 1.84
Y11758 Biglycan 3736 2.19 2.28 2.35
U83172 Paired-Ig-like receptor B 1662 3.35 2.16 1.28
AF063937 Serine (or cysteine) proteinase 371 4.35 1.39 1.04
inhibitor, CLADE B
L33416 Extracellular matrix protein 1 11967 2.74 2.07 1.96
X92960 Complement C1Q subcomponent, 3030 2.22 2.27 2.19
C chain precursor
AF053757 C3A anaphylatoxin chemotactic receptor 272 2.93 2.49 1.20
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