Table 1 of Chen, Mol Vis 2006; 12:360-366.


Table 1. Clinical features of the affected members

The age of onset was estimated according to individual medical history (asterisk). The double asterisk indicates that the maximum intraocular pressure IOP was not clear because of relatively advanced glaucoma at the time of first presentation. The triple asterisk indicates that the cup-disc ratio was not clear because of eyeball atrophy or cornea opacity. The sharp (hash mark) indicates that the visual field was not available because the patient had no light perception. The double sharp (hash marks) indicate that the member had surgery twice. The visual fields (VF) were graded for severity of visual field loss with a level grading scale [41]. Severity classification is leveled by the visual field score: mild (0-2), moderate (3-5), severe (6-8), and end stage (no light perception). Other abbreviations: NLP, no light perception; CF, count fingers.


                         Age of               Maximum                VF
Family           Age      onset    Visual       IOP     Cup-disc   grading                Medical
Member   Sex   (years)   (years)   acuity     (mmHg)     ratio      score    Severity     therapy
------   ---   -------   -------   --------   -------   --------   -------   ---------   ---------

 II:1     F      84       <30*     OD: NLP      **        ***         #      End stage   No
                                   OS: NLP      **        ***         #      End stage   No

 II:3     M      74       <31*     OD: NLP      38        ***         #      End stage   No
                                   OS: NLP      38        ***         #      End stage   No

 II:5     F      72       <18*     OD: NLP      **        ***         #      End stage   No
                                   OS: NLP      **        ***         #      End stage   No

III:3     M      54        27      OD: CF       30        1.0         8      Severe      Surgery
                                   OS: 0.8      30        0.4         1      Mild        Surgery

III:7     M      48        22      OD: 1.0      38        0.9         5      Moderate    Surgery##
                                   OS: 1.0      42        0.3         0      Mild        Surgery

III:13    F      42        22      OD: 1.0      37        0.5         1      Mild        Surgery
                                   OS: 1.0      38        0.4         0      Mild        Surgery

III:15    M      39        19      OD: 0.1      46        0.9         8      Severe      Surgery
                                   OS: 1.0      46        0.8         4      Moderate    Surgery

 IV:5     F      27        14      OD: 0.01     43        0.9         7      Severe      Surgery##
                                   OS: 0.8      54        0.6         4      Moderate    Surgery##

 IV:8     F      21        20      OD: 1.0      46        0.8         3      Moderate    Surgery
                                   OS: 1.0      46        0.5         0      Mild        Surgery

Chen, Mol Vis 2006; 12:360-366 <http://www.molvis.org/molvis/v12/a41/>
©2006 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535