Figure 5. Effect of high glucose on growth factor expression in human retinal endothelial cells (HRECs)

Exposure of HRECs to high glucose conditions resulted in a time-dependent increase in both vascular endothelial growth factor (VEGF) and insulin-like growth factor I (IGF-I) levels. Effect of high glucose on growth factor expression in human retinal endothelial cells (HRECs). Exposure of HRECs to high glucose conditions (green lines) resulted in a time-dependent increase in both VEGF (A) and IGF-I (B) levels greater than seen in low glucose conditions (red lines).