Figure 4 of
Spoerri, Mol Vis 2006;
12:32-42.
Figure 4. Percent of the human retinal endothelial cell (HREC) surface expressing the VEGF receptor
HRECs express lower levels of VEGFR-1 than VEGFR-2 basally. Reduction of VEGFR-1 results in a coordinate reduction of VEGFR-2, whereas reduction of VEGFR-2 has less of an impact on VEGFR-1 expression. The graph shows non-transfected HRECs (NT), HRECs transfected with the VEGFR-1 ribozyme (R1 Rz), and HRECs transfected with the VEGFR-2 ribozyme (R2 Rz), and HRECs tranfected with both the VEGFR-1 and VEGFR-2 ribozymes (R1+R2 Rz).