Figure 5. Degeneration of photoreceptors in rho (-/-) mice at P30

Fluorescent micrographs of vertical sections from a rho (-/-) mouse retina (C,D) and a control C57BL/6J (rho +/+) retina (A,B) probed with the rhodopsin antibody, B6-30 (A,C) and the PNA-Fluorescein (B,D) show the lack of rhodopsin protein and rod outer segments while cone's outer segments are still preserved. The ganglion layer (GL), inner nuclear layer (INL), outer nuclear layer (ONL), outer segment (OS), and inner segment (IS) are labeled. The scale bar represents 100 μm.