Figure 1 of
Yan, Mol Vis 2006;
12:205-214.
Figure 1. SDS-PAGE analysis of the effect of carnosine on fructose 6-phosphate-induced modifications of αL-crystallin
Fructose 6-phosphate (F6P) crosslinked αL-crystallin to form a dimer during a 4 d incubation but this crosslinking was decreased in the presence of carnosine. Lane M: Molecular weight marker. Lane A: control αL-crystallin at start. Lane B: αL-crystallin with 100 mM F6P at start. Lane C: control αL-crystallin at four days. Lane D: αL-crystallin with 100 mM F6P at four days. Lane E: αL-crystallin with 100 mM F6P and 100 mM carnosine at four days. Lane F: αL-crystallin with 100 mM F6P and 50 mM carnosine at four days.
