Table 2 of
Chen, Mol Vis 2006;
12:196-204.Table 2 of
Chen, Mol Vis 2006;
12:196-204.
Table 2. Results of immunofluorescence staining of corneal epithelial sheets
In eyes with recurrent corneal erosion (RCE), the manifestation of key adhesion molecules (integrin β1, integrin β4, laminin 5, and collagen VII) in epithelial sheets from the recurrent corneal erosion or the control eyes is summarized. Compared to control eyes, the most striking difference in affected eyes is the paucity of collagen VII, showing either patchy (discontinuous) staining or negative staining in immunofluorescence. Staining was characterized as positive (+) with a continuously linear pattern for antibody, patchy (+/-) with a discontinuous pattern for antibody, or negative (-) for antibody.
Patient Integrin Integrin Laminin Collagen
number β1 β4 5 VII
------- -------- -------- ------- --------
Epithelial sheets from recurrent corneal erosion
1 + + + -
2 + + + +/-
3 + + + +/-
4 + + + -
5 + + + -
6 + + + +/-
7 + + + -
8 + + + -
Mechanically separated epithelial sheet controls
9 + + + +
10 + + + +
11 + + + +
Partial lamellar keratectomized controls
12 + + + +
13 + + + +
14 + + + +
Corneoscleral rim controls
15 + + + +
16 + + + +
17 + + + +
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