Table 4 of Lai, Mol Vis 2006; 12:1687-1691.


Table 4. Relationship between the p53 gene mutation spectrum and BPDE-like DNA adduct levels

Mutations analyzed in this study were based on mutations found in prior pterygium samples (Tsai et al. [16]).


          BPDE-like
             DNA               p53 gene mutation
Patient    adduct     -----------------------------------
number     levels     Exon   Spectrum   Amino acid change
-------   ---------   ----   --------   -----------------
   1          0        8     G:C-C:G         Glu-Gln
   2        High       6     G:C-C:G         Arg-Pro
   3          0        7     T:A-A:T         Tyr-Asn
   4          0        5     C:G-T:A         His-Tyr
   5        High       7     1 bp del      Frame shift
   6          0        4     1-bp del      Frame shift
   7          0        6     A:T-T:A         Asp-Val
   8        High       6     G:C-T:A         Arg-Leu

Lai, Mol Vis 2006; 12:1687-1691 <http://www.molvis.org/molvis/v12/a192/>
©2006 Molecular Vision <http://www.molvis.org/molvis/>
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