Figure 2. Pedigree of the South African family with Ser911X in RP1

Squares and circles represent males and females, respectively. The diamond indicates several unaffected offspring who were not involved in this research project. Symbols for affected persons are solid. A diagonal line through the symbol indicates that the individual is deceased. Divorces are indicated by the double slashes. The individuals tested for the mutation are indicated by arrows, and the clinically asymptomatic mutation-carriers are indicated by asterisks.