Figure 7. Dose-dependent effect of t-butylhydroperoxide treatment on apical and basolateral secretion of vascular endothelial growth factor-A in polarized ARPE-19 monolayers

Secretion at 5 h treatment with t-butylhydroperoxide of vascular endothelial growth factor-A (VEGF-A) was significantly higher (p<0.05) versus the untreated controls. Processing of cells for VEGF secretion and calculations are given in Methods. Data are mean±SEM (n=4).