Figure 6. Effect of t-butylhydroperoxide on vascular endothelial growth factor-A and vascular endothelial growth factor-C secretion from ARPE-19 cells

A: Secretion of vascular endothelial growth factor-A (VEGF-A) in confluent control ARPE-19 cells and cells treated with varying doses of tBH for 5 h. Asterisk indicates VEGF-A secretion at 5 h with 150 μM t-butylhydroperoxide (tBH) was significantly (p<0.05) higher than the untreated controls. Data are mean±SEM (n= 4/time point in each group). B: Secretion of VEGF-C in confluent control ARPE-19 cells and cells treated with varying doses of tBH for 5 h. VEGF-C secretion after 5 h tBH treatment with varying doses was not significantly different from the untreated controls. Data are mean±SEM (n=4/time point in each group).