Figure 2 of
Zahir, Mol Vis 2006;
12:1606-1614.
Figure 2. Expression of proliferation, progenitor, glial, and bipolar cell markers by late RPCs before and after sorbitol treatment
Panels A through L show fluorescent images of Ki67, nestin, CRALBP, vimentin, GFAP and PKCα immunreactivity in combination with DAPI (4',6-Diamidino-2-phenylindole) staining before (A, C, E, G, I, K, 600x) and after (B, D, F, H, J, L, 600x) sorbitol treatment. Sorbitol induced RPCs to up-regulate CRALBP, GFAP, vimentin, and PKCα expression and adopt glial morphology. In contrast, sorbitol treatment resulted in a down regulation of Ki67 and nestin expression.