Figure 11 of Nickerson, Mol Vis 2006; 12:1565-1585.

Figure 11. A model of teleost IRBP locus evolution based on external unequal crossing over

An unequal crossing over event between the two chromatids of the IRBP gene leads to one chromatid bearing two copies of the IRBP gene. In subsequent steps, Repeat 4 is lost from the first gene and Repeats 2 and 3 are lost from the second gene. These steps produce a two-gene locus in head-to-tail orientation. Synteny is preserved in this model. GDF2 represents the growth differentiation factor 2 gene, and A8 represents the Annexin 8 gene.

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Nickerson, Mol Vis 2006; 12:1565-1585 <>
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