Figure 1 of
Bourges, Mol Vis 2006;
12:1461-1466.Figure 1 of
Bourges, Mol Vis 2006;
12:1461-1466.
Figure 1.
A: Debio088 formula prodrug consisting in a water-solubilizing moiety grafted on a free hydroxyl function of CsA. M=1570. B: Ex vivo conversion kinetics of Debio088 (closed square; 0.2% w/v in isotonic PBS solution) into CsA (closed triangle) incubated with rabbit tears (solid line) and isotonic PBS pH 7.4 (discontinueous line), mean±S.D., n=3.
