Figure 2. Comparison of cholestatrienol uptake by the rat retina via high density lipoprotein versus low density lipoprotein

Rats were injected intravenously with cholestatrienol-low density lipoprotein (CTL-LDL; 2 mg, blue) and cholestatrienol-high density lipoprotein (CTL-HDL; 1.5 mg, blue), then sacrificed 4 h post-injection (see Materials and Methods). Vibrotome sections were prepared and nuclei counter-stained with propidium iodide (red) before imaging by confocal microscopy. The retinas were imaged under identical conditions and at two different magnifications. A and B are control retinas from rats that received no injections. C and D are retinas from CTL-HDL injected rats. E and F are retinas from CTL-LDL injected rats.