Table 4 of
Pelzel, Mol Vis 2006;
Table 4. Summary of the changes in Rod:Cone opsin ratios
The fold change in the rod to red/green (or blue) opsin ratio in trephined samples of retina taken from the macula, mid-periphery, or periphery was calculated. Comparisons were made between the left and right eyes of normal animals or experimental and control eyes of the glaucoma monkeys. The data shown are the mean (±SEM) of several animals examined in each region (the number of animals examined in each region is denoted in parentheses). RC=the ratio of rod to red/green (or blue) cone opsin in control retinas. RE=the ratio of rod to red/green (or blue) cone opsin in experimental retinas. Overall, monkeys with experimental glaucoma show a significant increase in the RE/RC for red/green cone opsins in the mid-peripheral retina relative to control monkeys (*p=0.046). Sample sizes for the macular region were too small to make a statistical comparison.
Normal Glaucoma Animals Animals (RC1/RC2) (RE/RC) ------------- --------- -------- Red/Green Opsin Macula 1.8 1.8±0.5 (1) (3) Mid-Periphery 0.9±0.7 4.2±0.9* (2) (5) Periphery 1.8±0.9 2.0±0.5 (2) (4) Blue Opsin Macula 1.7 26.7±3.4 (1) (2) Mid-Periphery 2.3±1.0 12.1±2.1 (2) (4) Periphery 2.1±0.6 0.9±0.3 (2) (4)