Figure 4 of Jo, Mol Vis 2006; 12:1243-1249.


Figure 4.

H8 suppressed the development of CNV lesions at sites of laser induced rupture of Bruch's membrane. Choroidal flat-mounts were examined by fluorescence microscopy following immunostaining with PECAM-1 to identify vessels. A: Animals treated with control antibody showed large areas of CNV as compared to animals treated with either 10 or 30 mg/kg of H8. B: Quantitation of CNV lesion size in IgG and H8 treated samples. Both 10 mg/kg and 30 mg/kg treatments caused a statistically significant reduction in lesion size as compared to control untreated animals (the asterisk indicates a p<0.05 and the double asterisk denotes a p<0.001). Scale bar=20 μm.

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Jo, Mol Vis 2006; 12:1243-1249 <http://www.molvis.org/molvis/v12/a141/>
©2006 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535