Table 4 of
Kompella, Mol Vis 2006;
12:1185-1198.Table 4 of
Kompella, Mol Vis 2006;
12:1185-1198.
Table 4.
Influence of free ligands and low temperature on the corneal epithelial uptake of deslorelin- and transferrin-functionalized nanoparticles in the bovine ex vivo model. Free ligands were used at a concentration of 1 mg/ml in the nanoparticle drop administered. The data are expressed as mean±SD for n=3. The asterisk indicates a p<0.05 compared to controls at 37 °C.
Corneal epithelial uptake (60 min; ng/mg tissue/mg dose)
-----------------------------------------------------------
Particle type Control (37 °C) With free ligand (37 °C) Control (4 °C)
-------------- --------------- ------------------------ --------------
Deslorelin-CA 1361.8±611.9 579.5±237.4* 463.3± 54.5*
Transferrin-CA 1146.3±306.6 467.1±131.9* 307.1±124*
|