Table 2 of
Paez, Mol Vis 2006;
12:1048-1056.Table 2 of
Paez, Mol Vis 2006;
12:1048-1056.
Table 2. Functional annotation of the 30 top brain enriched genes
The top 30 genes with preferential brain expression in a retina-brain pool comparison are listed, with the corresponding identifiers, chromosomal location, expression ratio, and function. Hs represents Homo sapiens, Cfa represents Canis familiaris.
GenBank
Clone access Gene Gene ID Human Retina/brain
identifier number Dog chromosome location symbol number chromosome Unigene fold change Function
-------------- -------- -------------------------- --------- ------- ---------- ------------------- ------------ ------------------------------------
DR010023A20H05 DT541102 X:80,243,963-80,244,545 PLP1 5354 Xq22.2 Hs.1787 Cfa.3274 -25 Myelination
DR010027A10F10 DT542045 4:14,326,600-14,327,069 SPP1 6696 4q22.1 Hs.313 -20 Phosphoprotein
DR010005A20E04 DT537067 32:13,862,656-13,862,983 SPARCL1 8404 4q22.1 Hs.1424 -17 Extracellular matrix protein
DR010008A20A02 DT537874 20:40,129,412-40,129,709 NISCH 11188 3p21.1 Hs.435290 -16 Cytoskeleton and cellular components
DR010010B10C05 DT538398 6:62,422,039-62,422,316 LMO4 8543 1p22.3 Hs.436792 -11 Transcriptional regulator
DP010005000E06 DT536078 20:9,218,236-9,413,008 SYN2 6854 3p25 Hs.445503 -9 Neuronal phosphoproteins
DR010027B20A04 DT542218 16:55,443,443-55,443,919 GPM6A 2823 4q34.2 Hs.75819 -8 Myelin proteolipid
DR010014B20F03 DT539277 13:30,167,584-30,167,884 DDEF1 50807 8q24.21 Hs.106015 Cfa.10191 -6.5 Signal transduction
DR010015A20E10 DT539376 35:9,024,760-9,025,290 NRN1 51299 6p25.1 Hs.103291 -6.5 Neural activity
DR010019A20H03 DT540130 24:15,030,049-15,043,202 SNAP25 6616 2p12.2 Hs.167317 -6.5 Synaptic activity
DR010024A10E09 DT541302 26:31,587,239-31,587,700 SEPT5 5413 22q11.21 Hs.283743 -6 Nucleic acids acitivity
DR010024B10F05 DT541444 4:69,817,413-69,817,666 1q43 -6 EST
DR010026A20H08 DT541827 X:57,663,647-57,664,138 GDPD2 54857 Xq13.1 Hs.433812 -5 Cell differentiation
DR010013A10A11 DT538911 13:52,260,613-52,260,773 IGFBP7 3490 4q12 Hs.479808 -5 Insulin-like growth factor
DR010022A10B01 DT540751 24:15,694,097-15,694,559 C20orf103 24141 20p12.2 Hs.22920 -4.4 Protein precursor
DR010020A10B08 DT540252 17:62,843,281-62,843,815 MLLT11 10962 1q21.2 Hs.75823 -4.2 leukemogenesis
DR010025B10A02 DT541635 X:43,640,390-43,640,656 10q23.33 -4 Unknown
DR010026B20G05 DT541971 5:39,939,020-39,939,274 17p12 -4 Unknown
DR010025A21C11 DT541582 26:3,428,348-3,428,585 PXMP2 5827 12q24.33 Hs.430299 -3.6 Nucleic acitvity
DR010015A20E09 DT539375 15:5,881,332-5,881,851 PPT1 5538 1p34.2 Hs.3873 Cfa.10158 -3.6 Metabolism
DR010016B10H12 DT539539 20:48,103,437-48,103,712 19p13.11 -3 EST
DR010005B10E03 DT537156 2:79,096,079-79,096,475 CAMK2N1 55450 1p36.12 Hs.197922 -3 Metabolism
DR010012B20D10 DT539065 24:35,260,072-35,260,236 YWHAB 7529 20p13.12 Hs.279920 -2.5 Signal transduction
DR010020A20D02 DT540337 1:98,778,726-98,779,224 DIRAS2 54769 9q22.2 Hs.165636 -2.5 Metabolism
DR010024A20H05 DT541397 10:52,558,495-52,558,873 CALM2 805 2p21 Hs.468442 -2.5 Metabolism
DR010010A20G08 DT538371 1:111,515,746-111,516,031 CALM3 808 19q13.32 Hs.515487 -2.5 Metabolism
DR010013B10A11 DT538990 4:12,791,804-12,792,189 3p21.31 -2.5 EST
DR010013A10E12 DT539022 3:32,111,666-32,111,915 15q22.2 -2.5 EST
DR010028A20D02 DT542393 16:22,581,974-22,582,397 15q14 -2.5 EST
DR010012B20E05 DT538877 11,386,498-11,386,885 ATP2A2 488 12q24.11 Hs.506759 -2.5 Metabolism
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