Table 1 of
Paez, Mol Vis 2006;
12:1048-1056.
Table 1. Functional annotation of the top 30 retina-enriched genes
The top 30 genes with preferential retinal expression in a retina-brain pool comparisons are listed, with the corresponding identifiers, chromosomal location, expression ratio, and function. Hs represents Homo sapiens, Cfa represents Canis familiaris.
GenBank Clone access Gene Gene ID Human Retina/brain identifier number Dog chromosome location symbol number chromosome Unigene fold change Function -------------- -------- ------------------------ ------- ------- ------------- ------------------ ------------ ---------------------------- DR010009B10H06 DT538190 25:47,884,218-47,884,349 SAG 6295 2q37.1 Hs.308 Cfa.7077 37 Rhodopsin-mediated signaling DR010020A20B07 DT540322 14:21,958,280-21,958,543 GNAT1 2779 7q12.3 Hs.648519 Cfa.3191 36.5 Transport, visual system DR010017A21C10 DT539700 7:22,113,973-22,114,385 PDC 5132 1q31.1 Hs.580 Cfa.1202 36 Signal, visual system DR010018A20D11 DT539956 15:54,570,842-54,571,430 SFRP2 6423 4q31.3 Hs.481022 31.5 Unknown DR010017A21D08 DT539707 20:8,475,328-8,475,483 RHO 6010 3q21-q24 Hs.247565 Cfa.7396 27.5 Signal, visual system DR010024A10D06 DT541291 11:9,365,437-9,365,294 9q32 Hs.150406 26 EST DR010013B10A12 DT538991 3:94,958,572-9,958,849 PDE6B 399653 10p14 Hs.59872 Cfa.3793 25 Signal, visual system DR010015B10D11 DT539417 18:64,384,884-64,385,136 ROM1 6094 11q12.3 Hs.281564 24.5 Disk morphogenesis DR010030A20H09 DT543034 4:35,677,194-35,677,735 10q23.1 23 EST DR010008B20F12 DT538002 20:53,894,125-53,894,570 RDH8 50700 19p13.2 Hs.272405 21 Transport, visual system DR010023B10C07 DT541135 17:37,457,058-37,457,430 DUSP2 1844 2q11.2 Hs.1183 20.5 Nucleic acid metabolism DR010022A20E08 DT540832 12:51,422,323-51,422,562 6q15 Hs.520287 16 EST DR010018B20H08 DT540046 2:87,515,835-87,515,994 1p36.22 Hs.439194 11 EST DR010008B20G12 DT538006 7:69,939,004-69,939,305 CLUL1 27098 18p11.32 Hs.274959 Cfa.3516 9.30 Unknown DR010028B20H07 DT542573 27:4,960,724-4,961,087 NEUROD4 58158 12q13.2 Hs.131010 9.5 Metabolism DR010028B10E10 DT542509 17:51,086,234-51,086,428 NLR 4901 14q11.1-q11.2 Hs.89606 9 DNA, visual system DR010029A10E09 DT542612 6:19,524,381-19,524,521 KCTD13 253980 16p11.2 Hs.534590 9 DNA metabolism DR010009B10A10 DT538119 28:32,984,199-32,984,621 INPP5F 22876 10q26.12 Hs.369755 6.5 Metabolism DR010022B20B07 DT540940 8:35,335,208-35,335,594 OTX2 5015 14q21-q22 Hs.288655 6 Metabolism DR010021B20E07 DT540724 20:38,082,009-38,082,300 LRTM1 57408 3p14.3 Hs.554867 6 Sensory organ development DR010019B20C09 DT540148 14:58,294,157-58,294,685 7q31.2 Hs.239676 5 EST DR010014B20E10 DT539271 5:37,315,043-37,315,421 6p21.1 5 EST DR010011A20D01 DT538558 18:9,132,499-9,132,941 ECOP 81552 7p11.2 Hs.488307 4.5 Signal transducer activity DR010005B10H02 DT537179 5:59,339,081-59,339,539 GNB1 2782 1p36.33 Hs.430425 4.50 Signal transducer activity DR010016B20C07 DT539561 2:74,241,431-74,241,808 HMG-17 403686 13p25.1 Hs.477784 Cfa.3549 4 Nucleic acid DR010024B10C12 DT541427 22:7,990,538-7,990,876 HMGN2 3151 1p36.11 Hs.181163 4 Nucleic acid DR010017B10E11 DT539798 23:35,612,629-35,613,006 11q12.3 Hs.BC041359 4 EST DR010027B20E09 DT542265 12:67,236,366-67,236,647 GLTP 51228 12q24.11 Hs.381256 4 Transport DR010006B20G02 DT537497 2:78,953,814-78,954,066 DDOST 1650 1p36.12 Cfa.3884 3.5 Metabolism DR010029B10D10 DT542720 26:11,674,727-11,675,099 PPP1CC 5501 12q24.11 Hs.79081 Cfa.451 3.5 Metabolism DR010007A10G09 DT537586 33:26,792,981-26,793,197 3q13.33 Hs.333358 3.5 EST |