Table 4 of Kim, Mol Vis 2006; 12:1016-1021.


Table 4.

Associations of clinical characteristics with genotypes of endothelin receptor type A (EDNRA) polymorphisms in normal tension glaucoma patients. In the table, IOP indicates intraocular pressure, MD shows the mean deviation of program 30-2 of Humphrey visual field analyzer and PSD indicates the pattern standard deviation of program 30-2 of Humphrey visual field analyzer. The p values were determined using the Mann-Whitney U test.

  Polymorphism      Clinical characteristics          Genotype           p value
-----------------   ------------------------   -----------------------   -------
                                                 GG+GA          AA
                                               ----------   ----------
EDNRA: -231G>A      Baseline IOP (mm Hg)       16.2 ±2.3    14.0 ±2.8     0.047
                    Age at diagnosis (years)   43.9 ±10.3   48.7 ±8.0     0.285
                    MD (dB)                    -6.64±5.59   -5.47±3.18    0.839
                    PSD (dB)                    8.31±4.91    9.58±5.67    0.383

                                                 CC+CT          TT
                                               ----------   ----------
EDNRA: c.*1222C>T   Baseline IOP (mm Hg)       16.2 ±2.5    14.8 ±1.5     0.080
                    Age at diagnosis (years)   45.3 ±10.2   39.1 ±8.2     0.056
                    MD (dB)                    -6.68±5.43   -5.74±5.51    0.493
                    PSD (dB)                    8.62±4.85    7.33±5.61    0.482

Kim, Mol Vis 2006; 12:1016-1021 <http://www.molvis.org/molvis/v12/a114/>
©2006 Molecular Vision <http://www.molvis.org/molvis/>
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