Table 3 of
Kim, Mol Vis 2006;
12:1016-1021.Table 3 of
Kim, Mol Vis 2006;
12:1016-1021.
Table 3.
Distribution of the genotypes and alleles of endothelin-1 (EDN1), endothelin receptor type A (EDNRA), and endothelin receptor type B (EDNRB) polymorphisms in normal tension glaucoma patients and controls. The p value was obtained by χ2 or Fisher's exact test.
Gene/polymorphism Genotype p value Odds ratio Allele p value
-------------------------- ------------ -------- ----------- --------- -------
Endothelin-1
EDN1: c.-131dupA AA A- -- AA+A-/-- A -
-- -- -- -------- --- ---
Patients 46 21 0 0.3 113 21 0.96
Controls 70 29 1 169 31
EDN1:c.594G>T GG GT TT GG+GT/TT G T
-- -- -- -------- --- ---
Patients 31 29 7 0.76 91 43 0.27
Controls 56 35 9 147 53
Endothelin receptor type A
EDNRA: c.-231G>A GG GA AA GG+GA/AA G A
-- -- -- -------- --- ---
Patients 29 32 6 0.14 90 44 0.49
Controls 44 39 17 127 73
EDNRA: c.*70C>G CC CG GG CC+CG/GG C G
-- -- -- -------- --- ---
Patients 15 38 14 0.32 68 66 0.50
Controls 24 46 30 94 106
EDNRA: c.*1222C>T CC CT TT CC+CT/TT C T
-- -- -- -------- --- ---
Patients 31 26 10 0.028 3.33 88 46 0.22
Controls 49 46 5 (95% CI: 144 56
1.05-10.24)
Endothelin receptor type B
EDNRB: c.831A>G AA AG GG AA+AG/GG A G
-- -- -- -------- --- ---
Patients 24 30 13 0.46 78 56 0.76
Controls 28 57 15 113 87
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