	Affected members in family
Criteria	III:5	IV:1	IV:3	IV:4	IV:6	IV:7	IV:9	IV:11	IV:13	IV:15	V:2	V:3	V:6	V:7	V:8	V:9	V:11	V:13	V:14	VI:1	VI:2	VI:3

Major criteria

Congenital sensorineural hearing loss	-	-	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+
Pigmentary disturbances of the iris	+	-	-	-	-	-	-	-	-	-	-	+	-	-	-	-	+	-	-	+	+	-
Hair hypopigmentation	-	-	+	-	-	-	-	-	+	-	+	-	-	-	-	-	-	+	+	-	-	+
Dystopia canthorum	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
Affected first degree relative	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+

Minor criteria

Synophyrys	-	-	-	-	+	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-
Broad and high nasal root	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
Hypoplasia of alae nasi	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+
Premature graying of the hair	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-	+	-
Congenital leucoderma	-	+	+	+	+	+	-	+	+	+	-	-	+	+	+	+	-	+	+	-	-	-
