Table 3 of Cai, Mol Vis 2006; 12:1-14.


Table 3. Genes expressed in ARPE19 but not in adult human RPE (ahRPE)

Data were generated from Affymetrix U95Av2 DNA microarray analysis of four ahRPE and five ARPE19 samples. Numbers shown in ahRPE and ARPE19 columns are the mean values of DNA microarray chip densitometry scan signals. None of these nine genes are within the 2,500 most abundant gene list (data not shown).

Probe ID          Gene title           Symbol    ahRPE   ARPE19     Gene functions
---------   -----------------------   --------   -----   ------   -------------------
1562_g_at   dual specificity          DUSP8      27.0    154.9    inactivation of
            phosphatase 8                                         MAPK; protein
                                                                  dephosphorylation

32090_at    nicotinamide nucleotide   NMNAT2     20.4     65.9    phospholipid
            adenylyltransferase 2                                 biosynthesis; NAD
                                                                  biosynthesis

32753_at    splicing factor 3b,       SF3B3      39.6     73.4    mRNA splicing,
            subunit 3, 130 kDa                                    protein complex
                                                                  assembly

34801_at    ubiquitin specific        USP52      49.2     85.4    proteolysis
            protease 52

36458_at    KIAA1018 protein          KIAA1018   45.2    120.0    DNA repair

37580_at    SH3-domain GRB2-like 3    SH3GL3     25.7     50.3    signal transduction

38312_at    olfactomedin-like 2A      OLFML2A    21.4     96.9    latrotoxin receptor
                                                                  activity

39218_at    zinc finger protein 23    ZNF23      31.2     68.3    regulation of
            (KOX 16)                                              transcription,
                                                                  DNA-dependent

39590_at    amyloid β (A4)            APBA2      39.8    164.0    neurogenesis;
            precursor                                             protein transport
            protein-binding

Cai, Mol Vis 2006; 12:1-14 <http://www.molvis.org/molvis/v12/a1/>
©2006 Molecular Vision <http://www.molvis.org/molvis/>
ISSN 1090-0535