Table 2 of
Cai, Mol Vis 2006;
12:1-14.Table 2 of
Cai, Mol Vis 2006;
12:1-14.
Table 2. Genes expressed in adult human RPE (ahRPE) but not in ARPE19 cells
Data were generated from Affymetrix U95Av2 DNA microarray analysis of four ahRPE and five ARPE19 samples. Numbers shown in ahRPE and ARPE19 columns are the mean values of DNA microarray chip densitometry scan signals. Asterisk (*) indicates genes within 2,500 most abundant gene list (data not shown).
Probe ID Gene title Symbol ahRPE ARPE19 Gene functions
----------- ---------------------------- -------- ------ ------ -----------------------
1120_at glutathione S-transferase M3 GSTM3 112.8 31.2 metabolism
(brain)
1139_at guanine nucleotide binding GNA13 50.4 9.8 cell motility; signal
protein (G protein), α 13 transduction
1712_s_at mitogen-activated protein MAP2K4 53.5 17.0 proteinphosphorylation;
kinase kinase 4 signal transduction
2041_i_at v-abl Abelson murine ABL1 123.9 35.8 regulation of cell
leukemia viral oncogene cycle; induction of
homolog 1 apoptosis
32076_at Down syndrome critical DSCR1L1 87.0 22.1 calcium-mediated
region gene 1-like 1 signaling
32349_at annexin A10 ANXA10 134.5 18.5 negative regulation of
coagulation
32818_at tenascin C (hexabrachion) TNC 90.8 9.8 cell adhesion
33267_at ATPase, aminophospholipid ATP8A1 115.9 32.6 cation transport;
transporter (APLT) metabolism
33505_at retinoic acid receptor RARRES1 134.1 23.6 negative regulation of
responder (tazarotene cell proliferation
induced) 1
33803_at thrombomodulin THBD 92.4 23.7 blood coagulation
34363_at selenoprotein P, plasma, 1 SEPP1 68.0 5.7 response to oxidative
stress
34591_at* deiodinase, iodothyronine, DIO3 512.1 13.1 thyroxine
type III 5'-deiodinase activity
34666_at superoxide dismutase 2, SOD2 324.7 33.2 superoxide metabolism
mitochondrial
34823_at dipeptidylpeptidase 4 (CD26) DPP4 90.6 10.3 proteolysis; immune
response
35663_at neuronal pentraxin II NPTX2 93.2 3.7 synaptic transmission
35885_at ubiquitin specific protease USP9Y 65.6 5.0 ubiquitin-dependent
9 protein catabolism
35980_at phospholipase C, β 1 PLCB1 67.7 9.2 regulation of cell
(phosphoinositide-specific) cycle; lipid
catabolism
36312_at serine (or cysteine) SERPINB8 120.6 28.8 serine-type
proteinase inhibitor endopeptidase
inhibitor activity
36650_at cyclin D2 CCND2 113.9 5.5 regulation of cell
cycle; cytokinesis
37363_at metastasis suppressor 1 MTSS1 68.8 8.3 cell motility; cell
adhesion; neurogenesis
37402_at* ribonuclease, RNase A RNASE1 349.7 11.8 endonuclease activity
family, 1 (pancreatic)
38323_at carboxypeptidase, CPVL 111.3 4.4 proteolysis and
vitellogenic-like peptidolysis
38327_at silver homolog (mouse) SILV 181.6 39.2 melanin biosynthesis
from tyrosine
38355_at DEAD (Asp-Glu-Ala-Asp) box DDX3Y 218.7 6.9 nucleic acid binding
polypeptide 3, Y-linked hydrolase activity
38407_r_at* prostaglandin D2 synthase PTGDS 1056.6 10.3 prostaglandin
21 kDa (brain) biosynthesis;
transport
38469_at transmembrane 4 superfamily TM4SF3 247.5 11.3 protein amino acid
member 3 glycosylation
38528_at acetyl-Coenzyme A ACACA 118.3 44.9 fatty acid
carboxylase α biosynthesis;
metabolism
40097_at eukaryotic translation EIF1AY 53.0 4.2 protein biosynthesis;
initiation factor 1A, translational
Y-linked initiation
40583_at protein tyrosine PTPRJ 55.7 10.5 protein
phosphatase, receptor type, dephosphorylation;
J cell-cell signaling
40899_at* keratin 19 KRT19 632.1 6.1 structural molecule;
intermediate filament
41089_at ATPase, Ca++ transporting, ATP2B4 87.0 20.4 calcium ion transport;
plasma membrane 4 metabolism
41373_s_at microtubule-associated MAP1B 69.2 7.0 muscle development
protein 1B
434_at H1 histone family, member 0 H1F0 73.3 6.0 nucleosome assembly
759_at prostaglandin I2 PTGIS 134.3 19.4 electron transport;
(prostacyclin) synthase lipid metabolism
33339_g_at signal transducer and STAT1 187.9 19.1 regulation of cell
activator of transcription cycle; caspase
1, 91 kDa activation
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