Table 3 of
Mukhopadhyay, Mol Vis 2005;
11:792-797.Table 3 of
Mukhopadhyay, Mol Vis 2005;
11:792-797.
Table 3. Frequency distribution of the Met98Lys variant allele
Frequency distribution of variant alleles coding for Met98Lys in POAG and NTG patients in different population groups of the world. The table highlights the variability in the reported studies on the relative frequency of the allele coding for 98Lys among the population groups consisting mostly of Caucasians, east Asian, and south Asian. Such variability in the allelic distribution might be due to different gene pools in the population groups which determine the interaction of OPTN with other proteins contributing to the pathophysiology of the disease.
Patients
------------------
Population POAG (%) NTG (%) Controls (%) References
---------- -------- ------- ------------ ----------
Australia 7.4 0.0 3.2 [26]
Canada 12.2 0.0 3.9 [25]
France 4.6 0.0 4.5 [24]
Germany 0.0 6.3 7.0 [31]
Morocco 10.7 0.0 8.3 [24]
UK 4.4 10.6 3.2 [22]
USA 1.8 11.8 4.3 [14]
USA 5.1 5.3 7.2 [21]
USA 9.0 0.0 10.0 [23]
China 28.6 0.0 24.6 [27]
Japan 16.9 15.4 5.0 [30]
Japan 17.0 22.1 16.5 [29]
Japan 13.3 19.6 13.8 [28]
India 11.0 0.0 5.5 Present
study
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