Figure 3 of Yao, Mol Vis 2005; 11:758-763.

Figure 3. DNA sequence chromatograms and cosegregation analysis of the Q155X mutation with the disease phenotype

A: Forward sequence analysis of the normal and affected sequence of exon 6 of the CRYBB2 gene in this ADCC Chinese family. The C->T transition at position 475 converts the GLN codon 155 of CAG to an in-frame stop codon, TAG (Q155X). B: Restriction fragment length analysis showing that a gain of the novel SpeI site cosegregated with affected individuals heterozygous with the Q155X mutation (308, 202, and 153 bp) but not with unaffected individuals (308 and 202 bp).

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Yao, Mol Vis 2005; 11:758-763 <>
©2005 Molecular Vision <>
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