Figure 1. Pedigree and haplotype analysis of the cataractous Chinese family

Detailed pedigree of the ADCC Chinese family with the disease segregating with four microsatellite markers on chromosome 22 in five generations. In the pedigree, squares and circles symbolized males and females, respectively. Clear and blackened symbols denote unaffected and affected individuals, respectively. The affected haplotype is indicated by the filled box.