Figure 6 of Vasireddy, Mol Vis 2005; 11:665-676.

Figure 6. Formation of aggresomes at the MTOC

COS-7 cells were transfected with GFP-Ewt (A-C), GFP-Emut (D-F), GFP-Ewt and GFP-Emut (G-I), and mock transfected with transfection reagents alone (K) and were immunostained with antibodies to the centrosome marker, γ-tubulin. Staining of γ-tubulin is indicated with arrows (red). Overlays of images from first two columns on DAPI-stained nuclei of the respective cells (blue) were shown in panels C, F, I, and L. Physically interacting wild-type and mutant ELOVL4 formed aggresomes near MTOC (microtubule organizing center). The scale bar represents 5 μm.

(71 K)

Vasireddy, Mol Vis 2005; 11:665-676 <>
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