Figure 4 of
Yang, Mol Vis 2005;
Figure 4. Deletion mutant chaperone-like activity
The chaperone-like activity of the two NH2-terminal deletion mutants, both before and after thermal stress, was compared to that of recombinant αA-crystallin using the DTT-induced insulin denaturation assay. Both mutants exhibit similar levels of protection, albeit lower than recombinant αA-crystallin, before heat treatment. After cooling, LM51 shows the same level of activity as before treatment, but the chaperone-like activity of DM51 after treatment is essentially lost.