Table 3 of
Fan, Mol Vis 2005;
11:625-631.Table 3 of
Fan, Mol Vis 2005;
11:625-631.
Table 3. APOE polymorphisms observed in this study
The asterisk indicates that, compared to control subjects, when analyzed with non-ε4-carriers (genotypes 2/3+3/3), the frequency of ε4-carriers (genotypes 2/4+3/4+4/4) was significantly lower in NTG (OR=0.4, 95% CI: 0.2, 0.8; p=0.007).
Allele frequency (percentage) Genotype frequency (percentage)
------------------------------------ ------------------------------------
HTG NTG Control HTG NTG Control
Polymorphism Allele (n=588) (n=212) (n=562) Genotype (n=294) (n=106) (n=281)
------------ ------ ---------- ---------- ---------- -------- ---------- ---------- ----------
-491A>T T 28 (4.8) 5 (2.4) 15 (2.7) TT 3 (1.0) 1 (0.9) 1 (0.4)
A 560 (95.2) 207 (97.6) 547 (97.3) TA 22 (7.5) 3 (2.8) 13 (4.6)
AA 269 (91.5) 102 (96.2) 267 (95.0)
-427T>C C 5 (0.9) 1 (0.5) 5 (0.9) CC 1 (0.3) 0 (0.0) 0 (0.0)
T 583 (99.1) 211 (99.5) 557 (99.1) CT 3 (1.0) 1 (0.9) 5 (1.8)
TT 290 (98.6) 105 (99.1) 276 (98.2)
-219T>G G 222 (37.8) 69 (32.5) 187 (33.3) GG 35 (11.9) 14 (13.2) 24 (8.5)
T 366 (62.2) 143 (67.5) 375 (66.7) GT 152 (51.7) 41 (38.7) 139 (49.5)
TT 107 (36.4) 51 (48.1) 118 (42.0)
ε2/ε3/ε4* 4 39 (6.6) 8 (3.8) 52 (9.3) 4/4 1 (0.3) 0 (0.0) 0 (0.0)
2 63 (10.7) 16 (7.5) 48 (8.5) 2/4 5 (1.7) 0 (0.0) 8 (2.8)
3 486 (82.7) 188 (88.7) 462 (82.2) 3/4 32 (10.9) 8 (7.6) 44 (15.7)
2/3 58 (19.7) 16 (15.1) 40 (14.2)
3/3 198 (67.4) 82 (77.4) 189 (67.3)
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