Table 1 of
Mabuchi, Mol Vis 2005;
11:609-612.Table 1 of
Mabuchi, Mol Vis 2005;
11:609-612.
Table 1. Frequency of APOE genotypes and alleles
There were significant differences in the apolipoprotein E (APOE) genotype and allele frequencies between the open angle glaucoma (OAG) and control groups (p=0.0006 and p=0.0030, respectively; χ2 test). Each genotype is being compared to all other genotypes collectively. Data are presented as counts (percentages are in parentheses) and are calculated from the alleles of 310 patients and 179 controls (2 in each individual). Statistical tests reported in this table used Fisher's exact test.
OAG Control
patients subjects
Sample (n=310) (n=179) p value
------ ---------- ---------- -------
APOE genotypes
ε2ε2 0 (0) 0 (0)
ε2ε3 14 (4.5) 18 (10.1) 0.022
ε2ε4 2 (0.7) 0 (0) 0.53
ε3ε3 259 (83.5) 123 (68.7) 0.029
ε3ε4 35 (11.3) 38 (21.2) 0.0037
ε4ε4 0 (0) 0 (0)
APOE alleles
ε2 16 (2.6) 18 (5.0) 0.048
ε3 567 (91.4) 302 (84.4) 0.001
ε4 37 (6.0) 38 (10.6) 0.012
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