Table 2 of
Willoughby, Mol Vis 2005;
11:587-593.
Table 2. LOD scores for linkage between cataract with microcornea and 22q11.2-q12.2 markers
Two-point LOD scores for linkage in microsatellite markers across the β-crystallin gene cluster in the chromosomal regions 22q11.2-q12.2. The maximum two-point lod score was achieved for D22S1114 at θ=0. Zmax, the maximum lod score achieved, is given for each marker. Significant linkage was found with microsatellite marker D22S1144 with pair-wise lod score exceeding 3.0.
LOD score at recombination fraction --------------------------------------- Marker 0.0 0.05 0.10 0.20 0.30 0.40 Z Max θ Max -------- ---- ---- ---- ---- ---- ---- ----- ----- D22S1174 3.61 3.32 3.02 2.35 1.60 0.76 3.61 0 CRYB2A 2.41 2.23 2.04 1.63 1.17 0.63 2.41 0 D22S258 3.01 2.76 2.51 1.94 1.31 0.61 3.01 0 D22S1144 3.91 3.60 3.27 2.56 1.74 0.84 3.91 0 |