Table 2 of
Zhang, Mol Vis 2005;
11:554-560.
Table 2. Two-point linkage results for markers in the high myopia region at 4q22-4q27
Two-point linkage results for markers in the high myopia region at 4q22-4q27 support location of the disease locus between D4S1578 and D4S1612. Asterisks indicate markers included in the ABI PRISM MD10 linkage Mapping Set Version 2 which were used in the initial genome-wide scan. The haplotype referenced in the "Markers" column is the haplotype with markers D4S2986-D4S1572-D4S1564-D4S406-D4S1580-D4S402.
Position Lod score at θ --------------- ----------------------------------------------------- Markers cM Mb 0.00 0.01 0.05 0.10 0.20 0.30 0.40 Zmax θmax --------- ------ ------ ----- ----- ----- ----- ----- ----- ----- ---- ---- D4S414* 99.20 91.33 -∞ -0.74 0.44 0.77 0.78 0.53 0.23 0.83 0.15 D4S1557 99.20 95.32 -∞ -2.33 -1.06 -0.61 -0.25 -0.07 -0.01 0.00 0.55 D4S1578 103.10 97.44 -∞ 1.25 1.72 1.72 1.38 0.87 0.35 1.75 0.07 D4S2986 103.60 100.01 0.76 0.81 0.92 0.95 0.87 0.67 0.38 0.95 0.10 D4S1572* 106.30 104.13 1.54 1.52 1.42 1.30 1.03 0.74 0.40 1.54 0.00 D4S1564 111.10 108.73 3.11 3.05 2.80 2.47 1.78 1.04 0.33 3.11 0.00 D4S406* 115.80 112.08 2.11 2.07 1.91 1.70 1.26 0.79 0.32 2.11 0.00 D4S1580 120.80 116.49 0.50 0.54 0.64 0.66 0.57 0.38 0.13 0.66 0.10 D4S402* 123.50 120.51 1.37 1.41 1.48 1.46 1.28 0.96 0.54 1.48 0.07 D4S1612 123.50 122.68 -∞ 1.56 2.02 2.02 1.68 1.17 0.60 2.05 0.07 D4S2975 125.10 125.80 -∞ 1.56 2.02 2.02 1.68 1.17 0.60 2.05 0.07 Haplotype 3.61 3.55 3.30 2.98 2.28 1.52 0.72 3.61 0.00 |